BGC0000214: cosmomycin B biosynthetic gene cluster from Streptomyces olindensis
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Location: 1 - 14,080 nt. (total: 14,080 nt).
This entry is originally from NCBI GenBank DQ280500.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000214
Short description cosmomycin B biosynthetic gene cluster from Streptomyces olindensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
DQ280500.1
via
Compounds
  • cosmomycin B
Species Streptomyces olindensis [taxonomy]
References
Chemical products information
cosmomycin B Evidence:
Copy SMILES
C40H53N1O14
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABC00734.1
  • cosM
 1 - 365 (-) CosM
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    • ABC00735.1
    • cosL
    		 374 - 1000 (-) CosL
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      • ABC00725.1
      • cosk
      		 1074 - 2366 (-) CosK
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        • ABC00736.1
        • cosS
        		 2613 - 3176 (+) CosS
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          • ABC00732.1
          • cosY
          		 3284 - 4261 (+) CosY
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            • ABC00737.1
            • cosX
            		 4360 - 4713 (+) CosX
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              • ABC00726.1
              • cosB
              		 4710 - 5978 (+) CosB
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                • ABC00728.1
                • cosC
                		 5975 - 7219 (+) CosC
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                  • ABC00733.1
                  • cosE
                  		 7216 - 8250 (+) CosE
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                    • ABC00730.1
                    • cosF
                    		 8247 - 9296 (+) CosF
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                      • ABC00727.1
                      • cosT
                      		 9440 - 10690 (+) CosT
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                        • ABC00729.1
                        • cosG
                        		 10725 - 12005 (+) CosG
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                          • ABC00738.1
                          • cosH
                          		 12028 - 13011 (+) CosH
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                            • ABC00731.1
                            • cosI
                            		 13087 - 14076 (+) CosI
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                              Biosynthesis information
                              Annotation changelog

                              Entry version: 4

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-10-07
                              Update chemical activity to schema version 2.11
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 3

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-09-15
                              Updated bioactivity data
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 2

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2019-10-16
                              Migrated from v1.4
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              2019-10-16
                              Updated compound(s) information (NPAtlas curation)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2015-06-12
                              Submitted
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              Detailed domain annotation
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