BGC0000218: doxorubicin biosynthetic gene cluster from Streptomyces peucetius
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Location: 1 - 8,737 nt. (total: 8,737 nt).
This entry is originally from NCBI GenBank L35560.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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Gene details
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General information about the BGC
MIBiG accession BGC0000218
Short description doxorubicin biosynthetic gene cluster from Streptomyces peucetius
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: L35560.1
Compounds
  • doxorubicin
Species Streptomyces peucetius [taxonomy]
References
Chemical products information
doxorubicin
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C27H29N1O11
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAA65202.1
  • dnrH
 28 - 783 (+) daunorubicin-doxorubicin polyketide synthase
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  • AAA65203.1
  • dpsF
 918 - 1865 (-) daunorubicin-doxorubicin polyketide synthase
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  • AAA65204.1
  • dpsE
 1895 - 2680 (-) daunorubicin-doxorubicin polyketide synthase
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  • AAA65205.1
 2872 - 3261 (+) anthraquinol monooxygenase
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  • AAA65206.1
  • dpsA
 3258 - 4517 (+) daunorubicin-doxorubicin polyketide synthase
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  • AAA65207.1
  • dpsB
 4523 - 5800 (+) daunorubicin-doxorubicin polyketide synthase
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  • AAA65208.1
  • dpsC
 5797 - 6858 (+) daunorubicin-doxorubicin polyketide synthase
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  • AAA65209.1
  • dpsD
 6869 - 7882 (+) daunorubicin-doxorubicin polyketide synthase
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  • AAA65210.1
 7860 - 8720 (-)
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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