BGC0000220: enterocin biosynthetic gene cluster from Streptomyces maritimus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 22,511 nt. (total: 22,511 nt).
This entry is originally from NCBI GenBank AF254925.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000220
Short description enterocin biosynthetic gene cluster from Streptomyces maritimus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type II)
Loci
AF254925.1
via Knock-out studies, Enzymatic assays, Heterologous expression, Gene expression correlated with compound production
Compounds
  • enterocin
Species Streptomyces maritimus [taxonomy]
References
Chemical products information
enterocin Evidence:
Copy SMILES
C22H20O10
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAF81720.1
  • encE
 513 - 1004 (+) putative regulatory protein EncE
    copy AA seq
    copy Nt seq
    • AAF81721.1
    • encF
    		 1749 - 2600 (+) putative transcriptional regulator EncF
      copy AA seq
      copy Nt seq
      • AAF81722.1
      • encG
      		 2672 - 3163 (-) EncG
        copy AA seq
        copy Nt seq
        • AAF81723.1
        • encH
        		 3330 - 4937 (+) putative acyl-CoA ligase EncH
          copy AA seq
          copy Nt seq
          • AAF81724.1
          • encI
          		 4934 - 5710 (+) putative enoyl-CoA hydratase EncI
            copy AA seq
            copy Nt seq
            • AAF81725.1
            • encJ
            		 5856 - 7058 (-) putative beta-oxoacyl-CoA thiolase EncJ
              copy AA seq
              copy Nt seq
              • AAF81726.1
              • encK
              		 7073 - 7798 (-) putative O-methyl transferase EncK
                copy AA seq
                copy Nt seq
                • AAF81727.1
                • encD
                		 7826 - 8626 (-) putative ketoreductase EncD
                  copy AA seq
                  copy Nt seq
                  • AAF81728.1
                  • encA
                  		 8815 - 10086 (+) putative keto synthase alpha EncA
                    copy AA seq
                    copy Nt seq
                    • AAF81729.1
                    • encB
                    		 10083 - 11306 (+) putative keto synthase beta EncB
                      copy AA seq
                      copy Nt seq
                      • AAF81730.1
                      • encC
                      		 11354 - 11602 (+) putative acyl carrier protein EncC
                        copy AA seq
                        copy Nt seq
                        • AAF81731.1
                        • encL
                        		 11655 - 12677 (+) putative acyl transferase EncL
                          copy AA seq
                          copy Nt seq
                          • AAF81732.1
                          • encM
                          		 12734 - 14128 (+) putative FAD-dependent oxygenase EncM
                            copy AA seq
                            copy Nt seq
                            • AAF81733.1
                            • encN
                            		 14240 - 15808 (+) putative aryl-CoA ligase EncN
                              copy AA seq
                              copy Nt seq
                              • AAF81734.1
                              • encO
                              		 15850 - 16242 (-) EncO
                                copy AA seq
                                copy Nt seq
                                • AAF81735.1
                                • encP
                                		 16269 - 17840 (-) putative phenylalanine ammonia lyase EncP
                                  copy AA seq
                                  copy Nt seq
                                  • AAF81736.1
                                  • encQ
                                  		 18145 - 18390 (-) putative ferredoxin EncQ
                                    copy AA seq
                                    copy Nt seq
                                    • AAF81737.1
                                    • encR
                                    		 18384 - 19589 (-) putative p450 monooxygenase EncR
                                      copy AA seq
                                      copy Nt seq
                                      • AAF81739.1
                                      • encS
                                      		 19682 - 20329 (-) putative regulatory protein EncS
                                        copy AA seq
                                        copy Nt seq
                                        • AAF81738.1
                                        • encT
                                        		 20407 - 21855 (+) putative efflux protein EncT
                                          copy AA seq
                                          copy Nt seq
                                          Biosynthesis information
                                          Annotation changelog

                                          Entry version: 3

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Update chemical activity to schema version 2.11
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2019-10-16
                                          Migrated from v1.4
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2019-10-16
                                          Updated compound(s) information (NPAtlas curation)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2015-06-12
                                          Submitted
                                          • (ID: WV5D3525LKPE7P3F3GEDUNZX)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          Detailed domain annotation
                                          Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                          A domain glossary is available here, and an explanation of the visualisation is available here.
                                          Selected features only
                                          Show module domains
                                          Similar known gene clusters from MIBiG 4.0
                                          Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                          Click on reference genes to show details of similarities to genes within the current region.
                                          Click on an accession to open that entry in the MiBIG database.