BGC0000236: kinamycin biosynthetic gene cluster from Streptomyces murayamaensis
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Location: 1 - 37,227 nt. (total: 37,227 nt).
This entry is originally from NCBI GenBank AH012623.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000236
Short description kinamycin biosynthetic gene cluster from Streptomyces murayamaensis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AH012623.2
Compounds
  • kinamycin
Species Streptomyces murayamaensis [taxonomy]
References
Chemical products information
kinamycin
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C24H20N2O10
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAO65322.1
 1 - 2481 (+) putative vitamin B12-dependent ribonucleotide reductase
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  • AAO65323.1
 2699 - 3268 (-) unknown
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  • AAO65324.1
 3318 - 4145 (+) putative arylamine N-acetyltransferase
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  • AAO65325.1
 4179 - 4784 (+) unknown
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  • AAO65326.1
 4883 - 5542 (+) unknown
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  • AAO65327.1
 5555 - 6466 (+) putative hydrolase
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  • AAO65328.1
 6470 - 8029 (-) putative transmembrane efflux protein
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  • AAO65329.1
 8225 - 8860 (+) putative transcriptional regulator
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  • AAO65330.1
 8933 - 9643 (+) putative ribonuclease HII
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  • AAO65331.1
 9749 - 10357 (+) unknown
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  • AAO65332.1
 10605 - 11243 (-) unknown
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  • AAO65333.1
 11571 - 13730 (+) putative ATP-dependent DNA helicase
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  • AAO65334.1
 13811 - 14824 (+) unknown
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  • AAO65335.1
 14871 - 15269 (+) unknown
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  • AAO65336.1
 15280 - 15960 (+) putative bifunctional enzyme deaminase/reductase
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  • AAO65337.1
 16067 - 16381 (+) unknown
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  • AAO65338.1
 16503 - 18935 (+) unknown
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  • AAO65339.1
 19022 - 19318 (+) unknown
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  • AAO65340.1
  • kinR
 19336 - 19929 (-) putative TetR/AcrR-family transcriptional regulator
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  • AAO65341.1
  • kinU1
 20100 - 20519 (+) KinU1
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  • AAO65342.1
  • kinX
 20509 - 21093 (-) JadX-like protein
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  • AAO65343.1
  • kinO1
 21236 - 22705 (+) oxygenase-like protein
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  • AAO65344.1
  • kinG
 22756 - 23445 (+) anthrone oxidase-like protein
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  • AAO65345.1
  • kinI
 23886 - 24215 (+) JadI cyclase-like protein
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  • AAO65346.1
  • kinA
 24212 - 25486 (+) putative ketoacyl synthase
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  • AAO65347.1
  • kinB
 25483 - 26694 (+) putative chain length determinant
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  • AAO65348.1
  • kinC
 26733 - 27065 (+) putative acyl carrier protein
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  • AAO65349.1
  • kinE
 27091 - 27876 (+) putative ketoreductase
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  • AAO65350.1
  • kinD
 27903 - 28838 (+) cyclase/dehydratase-like protein
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  • AAO65351.1
  • kinOR
 28846 - 30318 (+) oxygenase reductase-like protein
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  • AAO65352.1
  • kinO2
 30426 - 31913 (+) oxygenase-like protein
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  • AAO65353.1
  • kinU
 32197 - 32946 (+) LanU-like protein
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  • AAO65354.1
  • kinJ
 32956 - 34236 (+) putative integral membrane efflux protein
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  • AAO65355.1
  • kinM
 34233 - 34922 (+) JadM phosphopantetheinyl transferase-like protein
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  • AAO65356.1
  • kinN
 34982 - 36562 (+) JadN decarboxylase-like protein
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  • AAO65357.1
  • kinX2
 36582 - 36887 (+) SimX2-like protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
3.0
  • Hidden contributor (ID: CUSGWVK3I4TVHJH7NHPFAP2L, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated the NCBI accession
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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