BGC0000236: kinamycin biosynthetic gene cluster from Streptomyces murayamaensis
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Location: 1 - 37,227 nt. (total: 37,227 nt).
This entry is originally from NCBI GenBank AH012623.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000236
Short description kinamycin biosynthetic gene cluster from Streptomyces murayamaensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AH012623.2
via
Compounds
  • kinamycin
Species Streptomyces murayamaensis [taxonomy]
References
Chemical products information
kinamycin Evidence:
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C24H20N2O10
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAO65322.1
 1 - 2481 (+) putative vitamin B12-dependent ribonucleotide reductase
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    • AAO65323.1
    		 2699 - 3268 (-) unknown
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      • AAO65324.1
      		 3318 - 4145 (+) putative arylamine N-acetyltransferase
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        • AAO65325.1
        		 4179 - 4784 (+) unknown
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          • AAO65326.1
          		 4883 - 5542 (+) unknown
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            • AAO65327.1
            		 5555 - 6466 (+) putative hydrolase
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              • AAO65328.1
              		 6470 - 8029 (-) putative transmembrane efflux protein
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                • AAO65329.1
                		 8225 - 8860 (+) putative transcriptional regulator
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                  • AAO65330.1
                  		 8933 - 9643 (+) putative ribonuclease HII
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                    • AAO65331.1
                    		 9749 - 10357 (+) unknown
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                      • AAO65332.1
                      		 10605 - 11243 (-) unknown
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                        • AAO65333.1
                        		 11571 - 13730 (+) putative ATP-dependent DNA helicase
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                          • AAO65334.1
                          		 13811 - 14824 (+) unknown
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                            • AAO65335.1
                            		 14871 - 15269 (+) unknown
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                              • AAO65336.1
                              		 15280 - 15960 (+) putative bifunctional enzyme deaminase/reductase
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                                • AAO65337.1
                                		 16067 - 16381 (+) unknown
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                                  • AAO65338.1
                                  		 16503 - 18935 (+) unknown
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                                    • AAO65339.1
                                    		 19022 - 19318 (+) unknown
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                                      • AAO65340.1
                                      • kinR
                                      		 19336 - 19929 (-) putative TetR/AcrR-family transcriptional regulator
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                                        • AAO65341.1
                                        • kinU1
                                        		 20100 - 20519 (+) KinU1
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                                          • AAO65342.1
                                          • kinX
                                          		 20509 - 21093 (-) JadX-like protein
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                                            • AAO65343.1
                                            • kinO1
                                            		 21236 - 22705 (+) oxygenase-like protein
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                                              • AAO65344.1
                                              • kinG
                                              		 22756 - 23445 (+) anthrone oxidase-like protein
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                                                • AAO65345.1
                                                • kinI
                                                		 23886 - 24215 (+) JadI cyclase-like protein
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                                                  • AAO65346.1
                                                  • kinA
                                                  		 24212 - 25486 (+) putative ketoacyl synthase
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                                                    • AAO65347.1
                                                    • kinB
                                                    		 25483 - 26694 (+) putative chain length determinant
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                                                      • AAO65348.1
                                                      • kinC
                                                      		 26733 - 27065 (+) putative acyl carrier protein
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                                                        • AAO65349.1
                                                        • kinE
                                                        		 27091 - 27876 (+) putative ketoreductase
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                                                          • AAO65350.1
                                                          • kinD
                                                          		 27903 - 28838 (+) cyclase/dehydratase-like protein
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                                                            • AAO65351.1
                                                            • kinOR
                                                            		 28846 - 30318 (+) oxygenase reductase-like protein
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                                                              • AAO65352.1
                                                              • kinO2
                                                              		 30426 - 31913 (+) oxygenase-like protein
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                                                                • AAO65353.1
                                                                • kinU
                                                                		 32197 - 32946 (+) LanU-like protein
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                                                                  • AAO65354.1
                                                                  • kinJ
                                                                  		 32956 - 34236 (+) putative integral membrane efflux protein
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                                                                    • AAO65355.1
                                                                    • kinM
                                                                    		 34233 - 34922 (+) JadM phosphopantetheinyl transferase-like protein
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                                                                      • AAO65356.1
                                                                      • kinN
                                                                      		 34982 - 36562 (+) JadN decarboxylase-like protein
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                                                                        • AAO65357.1
                                                                        • kinX2
                                                                        		 36582 - 36887 (+) SimX2-like protein
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                                                                          Biosynthesis information
                                                                          Annotation changelog

                                                                          Entry version: 4

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          2022-10-07
                                                                          Update chemical activity to schema version 2.11
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                          Entry version: 3

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          2022-09-15
                                                                          Updated the NCBI accession
                                                                          • (ID: CUSGWVK3I4TVHJH7NHPFAP2L)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          2022-09-15
                                                                          Updated bioactivity data
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                          Entry version: 2

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          2019-10-16
                                                                          Migrated from v1.4
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          2019-10-16
                                                                          Updated reference publication(s) (MIBiG Annotathon)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                          Entry version: 1

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          2015-06-12
                                                                          Submitted
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          Detailed domain annotation
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