BGC0000236 - 1 region(s) - antiSMASH results

BGC0000236 (Streptomyces murayamaensis)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	37,227	fluostatins M-Q	Polyketide	39%

BGC0000236 - Region 1 - T2PKS

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Location: 1 - 37,227 nt. (total: 37,227 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000236.1	1.00	Polyketide	kinamycin	Streptomyces murayamaensis
BGC0000231.1	0.60	Polyketide	griseusin	Streptomyces griseus
BGC0000234.1	0.51	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000248.1	0.48	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0001723.1	0.32	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000228.1	0.27	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000843.1	0.26	Other, , (, N, o, n, -, N, R, P, , b, e, t, a, -, l, a, c, t, a, m, )	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0002000.1	0.26	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0001904.1	0.26	Polyketide	fluostatin	Micromonospora rosaria
BGC0000215.1	0.26	Polyketide	curamycin	Streptomyces cyaneus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000236.1	1.00	Polyketide	kinamycin	Streptomyces murayamaensis
BGC0000231.1	0.84	Polyketide	griseusin	Streptomyces griseus
BGC0000234.1	0.79	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000248.1	0.78	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0001723.1	0.66	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000228.1	0.60	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000843.1	0.60	Other, , (, N, o, n, -, N, R, P, , b, e, t, a, -, l, a, c, t, a, m, )	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0002000.1	0.60	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0001904.1	0.59	Polyketide	fluostatin	Micromonospora rosaria
BGC0000215.1	0.59	Polyketide	curamycin	Streptomyces cyaneus

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 37227
Starter unit(s):: acetyl-CoA (Score: 0.0; E-value: 0)
Malonyl elongations:: 8|9 (Score: 717.5; E-value: 9.1e-219)
Product class(es):: angucycline
Product molecular weight(s):: acetyl-CoA_8: 381.35 Da
acetyl-CoA_9: 423.39 Da

kinA: KS (Score: 780.7; E-value: 7e-238)
kinB: CLF 8|9 (Score: 717.5; E-value: 9.1e-219)
kinC: ACP (Score: 140.1; E-value: 3.9e-44)
kinD: CYC C7-C12 (Score: 494.0; E-value: 3.2e-151)
kinE: KR C9 (Score: 481.8; E-value: 1.1e-147)
kinI: CYC C4-C17/C2-C19 (Score: 200.5; E-value: 5.6e-62)
kinO1: OXY (Score: 508.6; E-value: 4.2e-155)
kinO2: OXY (Score: 569.5; E-value: 1.4e-173)
kinOR: OXY (Score: 580.7; E-value: 5.6e-177)