BGC0000242: lysolipin I biosynthetic gene cluster from Streptomyces tendae
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 43,202 nt. (total: 43,202 nt).
This entry is originally from NCBI GenBank AM492533.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000242
Short description lysolipin I biosynthetic gene cluster from Streptomyces tendae
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AM492533.1
via
Compounds
  • lysolipin I
Species Streptomyces tendae [taxonomy]
References
Chemical products information
lysolipin I Evidence:
Copy SMILES
C29H24Cl1N1O11
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAM34331.1
151 - 516 (-) hypothetical protein
    copy AA seq
    copy Nt seq
    • CAM34332.1
    • llpRV
    554 - 1435 (+) putative DNA-binding protein
      copy AA seq
      copy Nt seq
      • CAM34333.1
      • llpY
      1622 - 2344 (+) hypothetical protein
        copy AA seq
        copy Nt seq
        • CAM34334.1
        • llpP
        2830 - 4383 (+) hypothetical protein
          copy AA seq
          copy Nt seq
          • CAM34335.1
          • llpRI
          4555 - 5169 (+) putative PadR family transcriptional regulator
            copy AA seq
            copy Nt seq
            • CAM34336.1
            • llpOI
            5269 - 6654 (+) putative FAD-depending monooxygenase
              copy AA seq
              copy Nt seq
              • CAM34337.1
              • llpJ
              6706 - 6912 (-) hypothetical protein
                copy AA seq
                copy Nt seq
                • CAM34338.1
                • llpOII
                6933 - 7244 (-) putative monooxygenase
                  copy AA seq
                  copy Nt seq
                  • CAM34339.1
                  • llpOIII
                  7241 - 7600 (-) putative monooxygenase
                    copy AA seq
                    copy Nt seq
                    • CAM34340.1
                    • llpZI
                    7600 - 8352 (-) putative 3-oxoacyl-ACP reductase
                      copy AA seq
                      copy Nt seq
                      • CAM34341.1
                      • llpB
                      8393 - 8854 (-) hypothetical protein
                        copy AA seq
                        copy Nt seq
                        • CAM34342.1
                        • llpCI
                        8866 - 9333 (-) putative polyketide cyclase
                          copy AA seq
                          copy Nt seq
                          • CAM34343.1
                          • llpD
                          9336 - 9596 (-) putative acyl carrier protein (ACP)
                            copy AA seq
                            copy Nt seq
                            • CAM34344.1
                            • llpE
                            9593 - 10837 (-) putative beta-ketoacyl synthase beta (CLF)
                              copy AA seq
                              copy Nt seq
                              • CAM34345.1
                              • llpF
                              10834 - 12123 (-) putative polyketide beta-ketoacyl synthase alpha
                                copy AA seq
                                copy Nt seq
                                • CAM34346.1
                                • llpCII
                                12120 - 12548 (-) putative polyketide cyclase
                                  copy AA seq
                                  copy Nt seq
                                  • CAM34347.1
                                  • llpCIII
                                  12545 - 12880 (-) putative polyketide cyclase
                                    copy AA seq
                                    copy Nt seq
                                    • CAM34348.1
                                    • llpU
                                    12986 - 13669 (-) putative short-chain dehydrogenase/reductase SDR
                                      copy AA seq
                                      copy Nt seq
                                      • CAM34349.1
                                      • llpG
                                      13825 - 14961 (+) putative inactive gylcosyltransferase
                                        copy AA seq
                                        copy Nt seq
                                        • CAM34350.1
                                        • llpA
                                        14993 - 16837 (+) putative amide synthase
                                          copy AA seq
                                          copy Nt seq
                                          • CAM34351.1
                                          • llpRII
                                          16870 - 17538 (+) putative transcriptional regulator, TNENA/THI-4 family
                                            copy AA seq
                                            copy Nt seq
                                            • CAM34352.1
                                            • llpOIV
                                            17573 - 18781 (+) putative cytochrome P450 hydroxylase
                                              copy AA seq
                                              copy Nt seq
                                              • CAM34353.1
                                              • llpK
                                              18790 - 18990 (+) putative 3Fe-S ferredoxin
                                                copy AA seq
                                                copy Nt seq
                                                • CAM34354.1
                                                • llpT
                                                18992 - 19360 (+) LlpT protein
                                                  copy AA seq
                                                  copy Nt seq
                                                  • CAM34355.1
                                                  • llpL
                                                  19428 - 20273 (-) hypothetical protein
                                                    copy AA seq
                                                    copy Nt seq
                                                    • CAM34356.1
                                                    • llpOV
                                                    20270 - 21463 (-) putative FAD-depending monooxygenase
                                                      copy AA seq
                                                      copy Nt seq
                                                      • CAM34357.1
                                                      • llpN
                                                      21469 - 22875 (-) putative major facilitator superfamily permease
                                                        copy AA seq
                                                        copy Nt seq
                                                        • CAM34358.1
                                                        • llpRIII
                                                        22945 - 23559 (-) putative transcriptional regulator
                                                          copy AA seq
                                                          copy Nt seq
                                                          • CAM34359.1
                                                          • llpOVI
                                                          23604 - 24803 (-) putative cytochrome P450 dependend monoxygenase
                                                            copy AA seq
                                                            copy Nt seq
                                                            • CAM34360.1
                                                            • llpMI
                                                            24844 - 25902 (-) putative O-methyltransferase
                                                              copy AA seq
                                                              copy Nt seq
                                                              • CAM34361.1
                                                              • llpOVII
                                                              25895 - 27118 (-) putative cytochrome P450 dependend hydroxylase
                                                                copy AA seq
                                                                copy Nt seq
                                                                • CAM34362.1
                                                                • llpMII
                                                                27123 - 28151 (-) putative methyltransferase
                                                                  copy AA seq
                                                                  copy Nt seq
                                                                  • CAM34363.1
                                                                  • llpOVIII
                                                                  28363 - 29988 (+) putative FAD-binding monooxygenase, PheA/TfdB family
                                                                    copy AA seq
                                                                    copy Nt seq
                                                                    • CAM34364.1
                                                                    • llpMIII
                                                                    29985 - 31001 (+) putative O-methyltransferase
                                                                      copy AA seq
                                                                      copy Nt seq
                                                                      • CAM34365.1
                                                                      • llpQ
                                                                      31050 - 31499 (-) hypothetical protein
                                                                        copy AA seq
                                                                        copy Nt seq
                                                                        • CAM34366.1
                                                                        • llpZII
                                                                        31496 - 32350 (-) putative F420-dependend reductase
                                                                          copy AA seq
                                                                          copy Nt seq
                                                                          • CAM34367.1
                                                                          • llpMIV
                                                                          32366 - 33367 (-) putative O-methyltransferase
                                                                            copy AA seq
                                                                            copy Nt seq
                                                                            • CAM34368.1
                                                                            • llpS
                                                                            33367 - 34248 (-) putative dehydrogenase
                                                                              copy AA seq
                                                                              copy Nt seq
                                                                              • CAM34369.1
                                                                              • llpV
                                                                              34245 - 34634 (-) hypothetical protein
                                                                                copy AA seq
                                                                                copy Nt seq
                                                                                • CAM34370.1
                                                                                • llpZIII
                                                                                34634 - 35371 (-) putative 3-oxoacyl-ACP reductase
                                                                                  copy AA seq
                                                                                  copy Nt seq
                                                                                  • CAM34371.1
                                                                                  • llpH
                                                                                  35393 - 36781 (-) putative non-heme halogenase
                                                                                    copy AA seq
                                                                                    copy Nt seq
                                                                                    • CAM34372.1
                                                                                    • llpRIV
                                                                                    36938 - 38779 (-) putative transcriptional activator, SARP family
                                                                                      copy AA seq
                                                                                      copy Nt seq
                                                                                      • CAM34373.1
                                                                                      • llpZIV
                                                                                      39912 - 40679 (+) putative reductase
                                                                                        copy AA seq
                                                                                        copy Nt seq
                                                                                        • CAM34374.1
                                                                                        • llpMV
                                                                                        40731 - 41411 (-) O-methyltransferase
                                                                                          copy AA seq
                                                                                          copy Nt seq
                                                                                          • CAM34375.1
                                                                                          • llpMVI
                                                                                          41508 - 42524 (-) putative O-methyltransferase
                                                                                            copy AA seq
                                                                                            copy Nt seq
                                                                                            • CAM34376.1
                                                                                            • ORF47
                                                                                            42785 - >43186 (-) putative terminal protein
                                                                                              copy AA seq
                                                                                              copy Nt seq
                                                                                              Biosynthesis information
                                                                                              Annotation changelog

                                                                                              Entry version: 4

                                                                                              Date
                                                                                              Changes
                                                                                              Submitters
                                                                                              Reviewers
                                                                                              Update chemical activity to schema version 2.11
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                              Entry version: 3

                                                                                              Date
                                                                                              Changes
                                                                                              Submitters
                                                                                              Reviewers
                                                                                              Updated bioactivity data
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                              Entry version: 2

                                                                                              Date
                                                                                              Changes
                                                                                              Submitters
                                                                                              Reviewers
                                                                                              Migrated from v1.4
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              Updated compound(s) information (NPAtlas curation)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                              Entry version: 1

                                                                                              Date
                                                                                              Changes
                                                                                              Submitters
                                                                                              Reviewers
                                                                                              Submitted
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                              Detailed domain annotation
                                                                                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                                                              A domain glossary is available here, and an explanation of the visualisation is available here.
                                                                                              Selected features only
                                                                                              Show module domains
                                                                                              Similar known gene clusters from MIBiG 4.0
                                                                                              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                                                              Click on reference genes to show details of similarities to genes within the current region.
                                                                                              Click on an accession to open that entry in the MiBIG database.