BGC0000252: nonactin biosynthetic gene cluster from Streptomyces griseus subsp. griseus
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Location: 1 - 15,559 nt. (total: 15,559 nt).
This entry is originally from NCBI GenBank AF074603.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000252
Short description nonactin biosynthetic gene cluster from Streptomyces griseus subsp. griseus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AF074603.2
Compounds
  • nonactin
Species Streptomyces griseus subsp. griseus [taxonomy]
References
Chemical products information
nonactin
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C40H64O12
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAD37450.1
  • nonK
 249 - 1526 (+) NonK
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  • AAD37451.1
  • nonJ
 1516 - 2796 (+) NonJ
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  • AAD37452.1
  • nonM
 2793 - 4394 (+) putative ketoacyl reductase
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  • AAD37453.1
  • nonE
 4391 - 5206 (+) putative ketoacyl reductase
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  • AAC26133.1
  • nonD
 5206 - 6915 (+) putative diester hydrolase
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  • AAC26134.1
  • nonL
 6912 - 8579 (+) putative nonactic acid:CoASH ligase
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  • AAC26135.1
  • nonS
 8576 - 9469 (+) nonactate synthase
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  • AAD37454.1
  • nonR
 9705 - 10544 (+) tetranactin resistance protein
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  • AAD37455.1
  • nonB
 10560 - 11066 (+) NonB
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  • AAD37456.1
  • nonC
 11255 - 12208 (+) NonC
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  • AAD37457.1
  • nonF
 12384 - 13088 (+) NonF
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  • AAD37458.1
  • nonI
 13237 - 13599 (+) putative acetoacetate reductase
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  • AAD37459.1
  • nonG
 13623 - 14351 (-) putative transcriptional repressor
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  • AAD37460.1
  • nonH
 14440 - 15270 (+) putative flavoprotein reductase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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