Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000254.1:
Cluster 1Polyketide125222

BGC0000254, oxytetracycline biosynthetic gene cluster from Streptomyces rimosus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: oxytetracycline
PubChem ID: 5280972
SMILES string: Copy to clipboard
Molecular formula: C22H24N2O9
Average molecular mass: 460.439 Da

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:
Type II

Gene cluster description

oxytetracycline (BGC0000254). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank DQ143963. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. Zhang W et al. (2006) Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase. Appl Environ Microbiol 72(4):2573-80. doi: