BGC0000254 - 1 region(s) - antiSMASH results

BGC0000254 (Streptomyces rimosus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	25,222	chlortetracycline	Polyketide	48%

BGC0000254 - Region 1 - T2PKS

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Location: 1 - 25,222 nt. (total: 25,222 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000254.1	1.00	Polyketide	oxytetracycline	Streptomyces rimosus
BGC0000248.1	0.43	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000231.1	0.37	Polyketide	griseusin	Streptomyces griseus
BGC0000234.1	0.34	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000228.1	0.31	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000272.1	0.28	Polyketide	spore pigment	Streptomyces collinus
BGC0000885.1	0.27	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000937.1	0.25	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000215.1	0.25	Polyketide	curamycin	Streptomyces cyaneus
BGC0000208.1	0.25	Polyketide	chelocardin	Amycolatopsis sulphurea

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000254.1	1.00	Polyketide	oxytetracycline	Streptomyces rimosus
BGC0000248.1	0.74	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000231.1	0.70	Polyketide	griseusin	Streptomyces griseus
BGC0000234.1	0.67	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000228.1	0.64	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000272.1	0.61	Polyketide	spore pigment	Streptomyces collinus
BGC0000885.1	0.60	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000937.1	0.59	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000215.1	0.58	Polyketide	curamycin	Streptomyces cyaneus
BGC0000208.1	0.58	Polyketide	chelocardin	Amycolatopsis sulphurea

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 25222
Starter unit(s):: malonamyl-CoA (Score: 1234.0; E-value: 0)
propionyl-CoA (Score: 363.0; E-value: 1.71e-128)
Malonyl elongations:: 8|9 (Score: 685.7; E-value: 3.9e-209)
Product class(es):: anthracycline
aureolic acid
tetracycline
Product molecular weight(s):: malonamyl-CoA_8: 440.46 Da
malonamyl-CoA_9: 482.50 Da
propionyl-CoA_8: 411.47 Da
propionyl-CoA_9: 453.50 Da

oxyA: KS (Score: 732.6; E-value: 2.9e-223)
oxyB: CLF 8|9 (Score: 685.7; E-value: 3.9e-209)
oxyC: ACP (Score: 120.4; E-value: 5.5e-38)
oxyD: AMID (Score: 1221.6; E-value: 0.0); AMID ELQ83270.1_Oxytetracycline_malonamyl-CoA (Score: 1234.0; E-value: 0.0)
oxyE: OXY (Score: 229.0; E-value: 2.8e-70)
oxyF: MET C6|C8 (Score: 569.9; E-value: 3.3e-174)
oxyI: CYC C1-C18|C2-C19 (Score: 236.1; E-value: 2.4e-73)
oxyJ: KR C9 (Score: 444.8; E-value: 2.1e-136)
oxyK: CYC C7-C12 (Score: 451.3; E-value: 3.1e-138)
oxyL: OXY (Score: 449.7; E-value: 3.2e-137)
oxyM: KR (Score: 136.8; E-value: 2.4e-42)
oxyN: CYC C5-C14/C3-C16 (Score: 452.8; E-value: 7.5e-139)
oxyP: AT (Score: 408.0; E-value: 6.9e-125); AT BAB72049.1_Aklavinone_propionyl-CoA (Score: 363.0; E-value: 1.71e-128)
oxyQ: AMIN (Score: 626.1; E-value: 4e-191)
oxyS: OXY (Score: 502.8; E-value: 2.4e-153)
oxyT: MET C2O|C2N (Score: 591.0; E-value: 1.5e-180)