BGC0000269: SF2575 biosynthetic gene cluster from Streptomyces sp. SF2575
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Location: 1 - 53,273 nt. (total: 53,273 nt).
This entry is originally from NCBI GenBank GQ409537.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000269
Short description SF2575 biosynthetic gene cluster from Streptomyces sp. SF2575
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type II)
  • saccharide (hybrid/tailoring)
Loci
GQ409537.1
via Knock-out studies, Enzymatic assays
Compounds
  • SF2575
Species Streptomyces sp. SF2575 [taxonomy]
References
Chemical products information
SF2575 Evidence: NMR [3]
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C40H43N1O15
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADE34480.1
 50 - 1327 (+) cysteine desulferase
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    • ADE34481.1
    		 1344 - 1808 (+) SUF system FeS assembly protein
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      • ADE34482.1
      		 1805 - 2143 (+) hypothetical protein
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        • ADE34483.1
        • ssfO2
        		 2224 - 3879 (-) SsfO2
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          • ADE34484.1
          • ssfM4
          		 4053 - 5084 (+) Methyltransferase
          • Methylation
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          • ADE34485.1
          • ssfV
          		 5087 - 6079 (+) SsfV
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            • ADE34486.1
            • ssfY4
            		 6217 - 6588 (-) SsfY4
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              • ADE34487.1
              • ssfM3
              		 6827 - 7876 (+) SsfM3
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                • ADE34488.1
                • ssfY3
                		 7873 - 8748 (+) SsfY3
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                  • ADE34489.1
                  • ssfY2
                  		 8817 - 9749 (+) SsfY2
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                    • ADE34490.1
                    • ssfY1
                    		 9830 - 10774 (-) SsfY1
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                      • ADE34491.1
                      • ssfU
                      		 10815 - 11600 (-) SsfU
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                        • ADE34492.1
                        • ssfS5
                        		 11711 - 12715 (+) SsfS5
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                          • ADE34493.1
                          • ssfL2
                          		 12718 - 14319 (+) SsfL2
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                            • ADE34494.1
                            • ssfX3
                            		 14417 - 15514 (-) SsfX3
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                              • ADE34495.1
                              • ssfL1
                              		 15623 - 17254 (-) SsfL1
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                                • ADE34496.1
                                • ssfX2
                                		 17303 - 18319 (-) SsfX2
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                                  • ADE34497.1
                                  • ssfQ
                                  		 18406 - 19614 (-) SsfQ
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                                    • ADE34498.1
                                    • ssfM2
                                    		 19848 - 20843 (-) Methyltransferase
                                    • Methylation
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                                    • ADE34499.1
                                    • ssfO1
                                    		 20880 - 22424 (-) SsfO1
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                                      • ADE34500.1
                                      • ssfP
                                      		 22528 - 23382 (+) SsfP
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                                        • ADE34501.1
                                        • ssfR
                                        		 23407 - 25044 (-) SsfR
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                                          • ADE34502.1
                                          • ssfT2
                                          		 25137 - 25766 (+) SsfT2
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                                            • ADE34503.1
                                            • ssfN
                                            		 26113 - 26991 (+) SsfN
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                                              • ADE34504.1
                                              • ssfK
                                              		 27008 - 27748 (+) SsfK
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                                                • ADE34505.1
                                                • ssfJ
                                                		 27739 - 28533 (+) SsfJ
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                                                  • ADE34506.1
                                                  • ssfI
                                                  		 28569 - 29816 (-) SsfI
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                                                    • ADE34507.1
                                                    • ssfH
                                                    		 30132 - 31457 (-) SsfH
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                                                      • ADE34508.1
                                                      • ssfM1
                                                      		 31776 - 32774 (-) Methyltransferase
                                                      • Methylation
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                                                      • ADE34509.1
                                                      • ssfG
                                                      		 33010 - 34029 (+) SsfG
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                                                        • ADE34510.1
                                                        • ssfS3
                                                        		 34103 - 35506 (+) SsfS3
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                                                          • ADE34511.1
                                                          • ssfS4
                                                          		 35503 - 36438 (+) SsfS4
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                                                            • ADE34512.1
                                                            • ssfS6
                                                            		 36669 - 37820 (-) SsfS6
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                                                              • ADE34525.1
                                                              • ssfF
                                                              		 38005 - 38976 (+) SsfF
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                                                                • ADE34513.1
                                                                • ssfE
                                                                		 39023 - 40654 (+) SsfE
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                                                                  • ADE34514.1
                                                                  • ssfX1
                                                                  		 40698 - 40919 (+) SsfX1
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                                                                    • ADE34515.1
                                                                    • ssfS1
                                                                    		 41065 - 42132 (+) SsfS1
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                                                                      • ADE34516.1
                                                                      • ssfS2
                                                                      		 42129 - 43112 (+) SsfS2
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                                                                        • ADE34517.1
                                                                        • ssfT1
                                                                        		 43176 - 43988 (-) SsfT1
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                                                                          • ADE34518.1
                                                                          • ssfA
                                                                          		 44931 - 46205 (+) SsfA
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                                                                            • ADE34519.1
                                                                            • ssfB
                                                                            		 46202 - 47440 (+) SsfB
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                                                                              • ADE34520.1
                                                                              • ssfC
                                                                              		 47491 - 47748 (+) SsfC
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                                                                                • ADE34521.1
                                                                                • ssfD
                                                                                		 47938 - 49791 (+) SsfD
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                                                                                  • ADE34522.1
                                                                                  		 49988 - 51838 (+) hypothetical protein
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                                                                                    • ADE34523.1
                                                                                    		 51841 - 52236 (-) hypothetical protein
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                                                                                      • ADE34524.1
                                                                                      		 52287 - 53255 (+) AraC family transcriptional regulator
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                                                                                        Biosynthesis information

                                                                                        No biosynthesis information available for this record.

                                                                                        Annotation changelog

                                                                                        Entry version: 5

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2024-06-04
                                                                                        MIBiG v4 annotathon
                                                                                        • (ID: P75FRHHCFPTCPYSP65VDVPHW)
                                                                                        • (ID: MGLE5JJ3S32DQA3YR5WPYH4W)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 4

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2022-10-07
                                                                                        Update chemical activity to schema version 2.11
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 3

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2022-09-15
                                                                                        Added version number to gene accession
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        2022-09-15
                                                                                        Removed gene names of 'No gene ID'
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        2022-09-15
                                                                                        Corrected gene identifiers
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        2022-09-15
                                                                                        Updated bioactivity data
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 2

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2019-10-16
                                                                                        Migrated from v1.4
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                        Entry version: 1

                                                                                        Date
                                                                                        Changes
                                                                                        Submitters
                                                                                        Reviewers
                                                                                        2015-06-12
                                                                                        Submitted
                                                                                        • (ID: BMUFDHMMOLZWQLUNJMQED2GP)
                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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