BGC0000332: cyanopeptolin biosynthetic gene cluster from Microcystis sp. NIVA-CYA 172/5
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Location: 1 - 31,880 nt. (total: 31,880 nt).
This entry is originally from NCBI GenBank DQ075244.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000332
Short description cyanopeptolin biosynthetic gene cluster from Microcystis sp. NIVA-CYA 172/5
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
DQ075244.1
via
Compounds
  • cyanopeptolin
Species Microcystis sp. NIVA-CYA 172/5 [taxonomy]
References
Chemical products information
cyanopeptolin Evidence:
Copy SMILES
C40H63N9O14S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAZ03548.1
  • mcnG
 85 - 1254 (-) McnG
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    • AAZ03549.1
    • mcnF
    		 1316 - 3385 (-) McnF
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      • AAZ03550.1
      • mcnA
      		 3953 - 7249 (+) McnA
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        • AAZ03551.1
        • mcnB
        		 7252 - 10569 (+) McnB
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          • AAZ03552.1
          • mcnC
          		 10566 - 24731 (+) McnC
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            • AAZ03553.1
            • mcnD
            		 24728 - 26605 (+) McnD
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              • AAZ03554.1
              • mcnE
              		 26602 - 30858 (+) McnE
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                Biosynthesis information

                Biosynthetic modules

                Name
                Unk01
                Type
                nrps-type1
                Genes
                mcnA
                Substrates
                glutamine (evidence: Structure-based inference [1])
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk02
                Type
                nrps-type1
                Genes
                mcnB
                Substrates
                threonine (evidence: Structure-based inference [1])
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk03
                Type
                nrps-type1
                Genes
                mcnC
                Substrates
                isoleucine (evidence: Structure-based inference [1])
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk04
                Type
                nrps-type1
                Genes
                mcnC
                Substrates
                3-amino-6-hydroxy-2-piperidone (evidence: Structure-based inference [1])
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk05
                Type
                nrps-type1
                Genes
                mcnC
                Substrates
                phenylalanine (evidence: Structure-based inference [1])
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk06
                Type
                nrps-type1
                Genes
                mcnC
                Substrates
                3-chlorotyrosine, tyrosine (evidence: Structure-based inference [1])
                Integrated Monomers
                Domains
                adenylation
                Name
                Unk07
                Type
                nrps-type1
                Genes
                mcnE
                Substrates
                glutamine (evidence: Structure-based inference [1])
                Integrated Monomers
                Domains
                adenylation
                Annotation changelog

                Entry version: 3

                Date
                Changes
                Submitters
                Reviewers
                2022-09-15
                Added NRP substrate specificities
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 2

                Date
                Changes
                Submitters
                Reviewers
                2019-10-16
                Migrated from v1.4
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                Entry version: 1

                Date
                Changes
                Submitters
                Reviewers
                2015-06-12
                Submitted
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                Detailed domain annotation
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