BGC0000347: equibactin biosynthetic gene cluster from Streptococcus equi subsp. equi
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 36,024 - 59,836 nt. (total: 23,813 nt).
This entry is originally from NCBI GenBank AM909652.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000347
Short description equibactin biosynthetic gene cluster from Streptococcus equi subsp. equi
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AM909652.1
36024 - 59836
via
Compounds
  • equibactin
Species Streptococcus equi subsp. equi [taxonomy]
References
Chemical products information
equibactin Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SEQ1246
  • CAP20360.1
  • eqbA
 36024 - 36404 (+) putative iron-dependent regulatory protein
    copy AA seq
    copy Nt seq
    • SEQ1245
    • CAP20361.1
    • eqbB
    		 36633 - 37382 (+) putative non-ribosomal peptide synthesis thioesterase
      copy AA seq
      copy Nt seq
      • SEQ1244
      • CAP20362.1
      • eqbC
      		 37369 - 38052 (+) putative 4'-phosphopantetheinyl transferase superfamily protein
        copy AA seq
        copy Nt seq
        • SEQ1243
        • CAP20363.1
        • eqbD
        		 38061 - 39644 (+) equibactin siderophore biosynthetic protein
          copy AA seq
          copy Nt seq
          • SEQ1242
          • CAP20364.1
          • eqbE
          		 39659 - 45730 (+) equibactin equibactin nonribosomal peptide synthase protein
            copy AA seq
            copy Nt seq
            • SEQ1241
            • CAP20365.1
            • eqbF
            		 45727 - 47853 (+) equibactin biosynthetic protein
              copy AA seq
              copy Nt seq
              • SEQ1240
              • CAP20366.1
              • eqbG
              		 47837 - 51655 (+) equibactin nonribosomal peptide synthase protein
                copy AA seq
                copy Nt seq
                • SEQ1239
                • CAP20367.1
                • eqbH
                		 51645 - 52232 (+) putative membrane protein
                  copy AA seq
                  copy Nt seq
                  • SEQ1238
                  • CAP20368.1
                  • eqbI
                  		 52234 - 52905 (+) putative transmembrane protein
                    copy AA seq
                    copy Nt seq
                    • SEQ1237
                    • CAP20369.1
                    • eqbJ
                    		 52919 - 54295 (+) putative ABC transporter ATP-binding component
                      copy AA seq
                      copy Nt seq
                      • SEQ1236
                      • CAP20370.1
                      • eqbK
                      		 54318 - 56075 (+) ABC transporter, ATP-binding membrane protein
                        copy AA seq
                        copy Nt seq
                        • SEQ1235
                        • CAP20371.1
                        • eqbL
                        		 56080 - 57825 (+) ABC transporter ATP-binding membrane protein
                          copy AA seq
                          copy Nt seq
                          • SEQ1234
                          • CAP20372.1
                          • eqbM
                          		 57845 - 58909 (+) putative oxidoreductase
                            copy AA seq
                            copy Nt seq
                            • SEQ1233
                            • CAP20373.1
                            • eqbN
                            		 58931 - 59836 (+) putative membrane protein
                              copy AA seq
                              copy Nt seq
                              Biosynthesis information

                              Biosynthetic modules

                              Name
                              Unk01
                              Type
                              nrps-type1
                              Genes
                              eqbD
                              Substrates
                              salicylic acid (evidence: Sequence-based prediction, Structure-based inference)
                              Integrated Monomers
                              Domains
                              adenylation
                              Name
                              Unk02
                              Type
                              nrps-type1
                              Genes
                              eqbE
                              Substrates
                              cysteine (evidence: Sequence-based prediction, Structure-based inference)
                              Integrated Monomers
                              Domains
                              adenylation
                              Annotation changelog

                              Entry version: 4

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-10-07
                              Update chemical activity to schema version 2.11
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 3

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-09-15
                              Updated bioactivity data
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              2022-09-15
                              Added NRP substrate specificities
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 2

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2019-10-16
                              Migrated from v1.4
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2015-06-12
                              Submitted
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              Detailed domain annotation
                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                              A domain glossary is available here, and an explanation of the visualisation is available here.
                              Selected features only
                              Show module domains
                              Similar known gene clusters from MIBiG 4.0
                              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                              Click on reference genes to show details of similarities to genes within the current region.
                              Click on an accession to open that entry in the MiBIG database.