BGC0000348: ergovaline biosynthetic gene cluster from Epichloe festucae var. lolii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 19,379 nt. (total: 19,379 nt).
This entry is originally from NCBI GenBank EF125025.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000348
Short description ergovaline biosynthetic gene cluster from Epichloe festucae var. lolii
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
EF125025.1
via
Compounds
  • ergovaline
Species Epichloe festucae var. lolii [taxonomy]
References
Chemical products information
ergovaline Evidence:
Copy SMILES
C29H35N5O5
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABM91453.1
  • easH
1 - 558 (+) putative dioxygenase
    copy AA seq
    copy Nt seq
    • ABM91449.1
    • easA
    1019 - 2161 (-) putative oxidoreductase
      copy AA seq
      copy Nt seq
      • ABM91452.1
      • easG
      3517 - 4575 (+) conserved protein EasG
        copy AA seq
        copy Nt seq
        • ABM91451.1
        • easF
        4619 - 5721 (-) conserved protein EasF
          copy AA seq
          copy Nt seq
          • ABM91450.1
          • easE
          6190 - 8140 (-) putative oxidoreductase
            copy AA seq
            copy Nt seq
            • ABM91454.1
            • lpsB
            9411 - 13540 (+) lysergyl peptide synthetase LpsB
              copy AA seq
              copy Nt seq
              Biosynthesis information
              Annotation changelog

              Entry version: 3

              Date
              Changes
              Submitters
              Reviewers
              Cleaned up synonym list
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 2

              Date
              Changes
              Submitters
              Reviewers
              Migrated from v1.4
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              Updated compound(s) information (MIBiG Annotathon)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              Updated compound(s) information (NPAtlas curation)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

              Entry version: 1

              Date
              Changes
              Submitters
              Reviewers
              Submitted
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              Detailed domain annotation
              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
              A domain glossary is available here, and an explanation of the visualisation is available here.
              Selected features only
              Show module domains
              Similar known gene clusters from MIBiG 4.0
              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
              Click on reference genes to show details of similarities to genes within the current region.
              Click on an accession to open that entry in the MiBIG database.