BGC0000356 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000356 (Aspergillus fumigatus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS,indole	1	27,708	notoamide A	NRP	22%

BGC0000356 - Region 1 - NRPS,indole

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Location: 1 - 27,708 nt. (total: 27,708 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
indole: (indsynth or dmat or indole_PTase)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 27,709
Label		BGC0000356

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000356.1	1.51	NRP, Alkaloid	verruculogen, fumitremorgin B, fumitremorgin c, tryprostatin A, tryprostatin B, demethoxyfumitremorgin C, brevianamide F	Aspergillus fumigatus
BGC0001241.1	0.67	Terpene	ergotamine	Claviceps fusiformis
BGC0001267.1	0.67	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0001375.1	0.61	Terpene	penitrem A, penitrem B, penitrem C, penitrem D, penitrem E, penitrem F	Penicillium simplicissimum
BGC0001604.1	0.60	Terpene	gibberellin	Fusarium fujikuroi
BGC0001260.1	0.58	Terpene	terpendole E	Tolypocladium album
BGC0001777.1	0.56	Terpene	shearinine D	Escovopsis weberi
BGC0001775.1	0.55	Terpene	sespendole	Cordana terrestris
BGC0000685.1	0.55	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0001969.1	0.53	Terpene	asperterpenoid A	Talaromyces wortmannii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000356.1	1.00	NRP, Alkaloid	verruculogen, fumitremorgin B, fumitremorgin c, tryprostatin A, tryprostatin B, demethoxyfumitremorgin C, brevianamide F	Aspergillus fumigatus
BGC0000348.1	0.67	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001241.1	0.67	Terpene	ergotamine	Claviceps fusiformis
BGC0001267.1	0.67	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0001249.1	0.67	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900.1	0.64	Other	ferrichrome	Aspergillus oryzae
BGC0001375.1	0.64	Terpene	penitrem A, penitrem B, penitrem C, penitrem D, penitrem E, penitrem F	Penicillium simplicissimum
BGC0001604.1	0.64	Terpene	gibberellin	Fusarium fujikuroi
BGC0001260.1	0.63	Terpene	terpendole E	Tolypocladium album
BGC0001261.1	0.62	NRP	AM-toxin	Alternaria alternata

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27708:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 26956:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ftmA

Search NORINE for peptide: strict or relaxed

AMP-binding (54..457): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvmfigavnk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1148..1548): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvyfvggick
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)