BGC0000365: glycopeptidolipid biosynthetic gene cluster from Mycolicibacterium smegmatis MC2 155
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Location: 1 - 67,229 nt. (total: 67,229 nt).
This entry is originally from NCBI GenBank AY439015.3.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000365
Short description glycopeptidolipid biosynthetic gene cluster from Mycolicibacterium smegmatis MC2 155
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AY439015.3
via
Compounds
  • glycopeptidolipid
Species Mycolicibacterium smegmatis MC2 155 [taxonomy]
References
Chemical products information
glycopeptidolipid Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABB72060.1
  • mmpS4
 1 - 420 (+) MmpS4
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    • ABB72061.1
    • mmpl4a
    		 417 - 3299 (+) Mmpl4a
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      • ABB72062.1
      • mmpL4b
      		 3309 - 6293 (+) Mmpl4b
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        • ABB72063.1
        • rv1174c
        		 6364 - 6702 (-) Rv1174c
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          • ABB72064.1
          • rmlA
          		 6886 - 7752 (-) RmlA
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            • ABB72065.1
            • gtf3
            		 8259 - 9527 (+) Gtf3
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              • ABB72066.1
              • rmlB
              		 9588 - 10718 (+) RmlB
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                • ABB72067.1
                • rmt2
                		 10793 - 11701 (+) Rmt2
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                  • ABB72068.1
                  • rmt4
                  		 11953 - 12753 (+) Rmt4
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                    • ABB72069.1
                    • gtf1
                    		 12787 - 14055 (+) Gtf1
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                      • ABB72070.1
                      • atf1
                      		 14160 - 15344 (+) Atf1
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                        • ABB72071.1
                        • rmt3
                        		 15416 - 16306 (+) Rmt3
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                          • ABB72072.1
                          • gtf2
                          		 16344 - 17597 (-) Gtf2
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                            • ABB72073.1
                            • fmt
                            		 17800 - 18624 (+) Fmt
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                              • AAT01803.2
                              • tnpA
                              		 20042 - 21283 (+) TnpA
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                                • AAT01804.2
                                • tnpR
                                		 21291 - 22031 (-) TnpR
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                                  • AAT01805.1
                                  • mbtH
                                  		 22295 - 22525 (+) MbtH
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                                    • AAT01806.1
                                    • mps1
                                    		 22554 - 32849 (+) non-ribosomal peptide synthetase
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                                      • AAT01807.1
                                      • mps2
                                      		 32846 - 40525 (+) non-ribosomal peptide synthetase
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                                        • AAT01808.1
                                        • gap
                                        		 40542 - 41360 (+) integral membrane protein
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                                          • AAT01809.1
                                          • sap
                                          		 41462 - 41872 (+) sigma associated protein
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                                            • AAT01810.1
                                            • ecf
                                            		 41881 - 43056 (+) extra cytoplasmic sigma factor
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                                              • AAU04876.1
                                              • fadE5
                                              		 43099 - 44934 (-) acyl-coA-dehydrogenase
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                                                • AAU04877.1
                                                • Rv0926c
                                                		 45172 - 46260 (+) conserved hypothetical protein
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                                                  • AAU04878.1
                                                  • pks
                                                  		 46271 - 57229 (-) polyketide synthase
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                                                    • ABC70852.1
                                                    • papA3
                                                    		 57279 - 58892 (+) PapA3
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                                                      • ABC70853.1
                                                      • mmpL
                                                      		 58926 - 61934 (+) MmpL
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                                                        • ABC70854.1
                                                        • fadD28
                                                        		 62044 - 63753 (+) FadD28
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                                                          • ABC70855.1
                                                          • pE
                                                          		 63815 - 64966 (+) PE
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                                                            • ABC70856.1
                                                            		 64971 - 65660 (-) Gap-like
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                                                              Biosynthesis information

                                                              Biosynthetic modules

                                                              Name
                                                              Unk01
                                                              Type
                                                              nrps-type1
                                                              Genes
                                                              mps1
                                                              Substrates
                                                              phenylalanine (evidence: Structure-based inference [1], [3])
                                                              Integrated Monomers
                                                              Domains
                                                              adenylation
                                                              Name
                                                              Unk02
                                                              Type
                                                              nrps-type1
                                                              Genes
                                                              mps1
                                                              Substrates
                                                              threonine (evidence: Structure-based inference [1], [3])
                                                              Integrated Monomers
                                                              Domains
                                                              adenylation
                                                              Name
                                                              Unk03
                                                              Type
                                                              nrps-type1
                                                              Genes
                                                              mps2
                                                              Substrates
                                                              alanine (evidence: Structure-based inference [1], [3])
                                                              Integrated Monomers
                                                              Domains
                                                              adenylation
                                                              Name
                                                              Unk04
                                                              Type
                                                              nrps-type1
                                                              Genes
                                                              mps2
                                                              Substrates
                                                              alaninol (evidence: Structure-based inference [1], [3])
                                                              Integrated Monomers
                                                              Domains
                                                              adenylation
                                                              Annotation changelog

                                                              Entry version: 3

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              2022-09-15
                                                              Added NRP substrate specificities
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                              Entry version: 2

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              2019-10-16
                                                              Migrated from v1.4
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                              Entry version: 1

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              2015-06-12
                                                              Submitted
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              Detailed domain annotation
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