Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000373.1:
Cluster 1NRP118318

BGC0000373, holomycin biosynthetic gene cluster from Streptomyces clavuligerus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: holomycin
PubChem ID: 10262683
SMILES string: Copy to clipboard
Molecular formula: C7H6N2O2S2
Average molecular mass: 214.257 Da

Class-specific details

Biosynthetic class(es):

Gene cluster description

holomycin (BGC0000373). Gene Cluster 1. Biosynthetic class = NRP. GenBank CM000913, positions 6204480-6222797. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Li B, Walsh CT. (2010) Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus. Proc Natl Acad Sci U S A 107(46):19731-5. doi: