BGC0000373 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000373 (Streptomyces clavuligerus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	18,318	thiolutin	NRP	28%

BGC0000373 - Region 1 - NRPS

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Location: 1 - 18,318 nt. (total: 18,318 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 18,319
Label		BGC0000373

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000373.1	0.96	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001778.1	0.29	Other	showdomycin	Streptomyces showdoensis
BGC0002091.1	0.28	NRP	holomycin	Yersinia ruckeri ATCC 29473
BGC0001399.1	0.25	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000347.1	0.22	NRP	equibactin	Streptococcus equi subsp. equi
BGC0001132.1	0.22	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001135.1	0.22	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000410.1	0.22	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001825.1	0.22	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000427.1	0.22	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000373.1	0.99	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001778.1	0.63	Other	showdomycin	Streptomyces showdoensis
BGC0002091.1	0.62	NRP	holomycin	Yersinia ruckeri ATCC 29473
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000347.1	0.55	NRP	equibactin	Streptococcus equi subsp. equi
BGC0001132.1	0.55	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001135.1	0.55	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000410.1	0.55	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001825.1	0.55	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000427.1	0.54	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 18318:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

SCLAV_5271

Search NORINE for peptide: strict or relaxed

AMP-binding (503..907): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)