Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000382.1:
Cluster 1NRP119400

BGC0000382, lipstatin biosynthetic gene cluster from Streptomyces toxytricini. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: lipstatin
PubChem ID: 6438672
SMILES string: Copy to clipboard
Molecular formula: C29H49NO5
Average molecular mass: 491.713 Da

Class-specific details

Biosynthetic class(es):
NRP

Gene cluster description

lipstatin (BGC0000382). Gene Cluster 1. Biosynthetic class = NRP. GenBank KJ872771. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. Bai T et al. (2014) Operon for biosynthesis of lipstatin, the Beta-lactone inhibitor of human pancreatic lipase. Appl Environ Microbiol 80(24):7473-83. doi: 10.1128/AEM.01765-14. Epub