BGC0000444: thaxtomin A biosynthetic gene cluster from Streptomyces turgidiscabies Car8
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Location: 12,536 - 33,158 nt. (total: 20,623 nt).
This entry is originally from NCBI GenBank AY707081.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000444
Short description thaxtomin A biosynthetic gene cluster from Streptomyces turgidiscabies Car8
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AY707081.1
12536 - 33158
via
Compounds
  • thaxtomin A
Species Streptomyces turgidiscabies Car8 [taxonomy]
References
Chemical products information
thaxtomin A Evidence:
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C22H22N4O6
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • stPAI021
  • AAW49313.1
  • nos
 12536 - 13738 (-) nitric oxide synthase
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    • stPAI022
    • AAW49314.1
    		 13770 - 14990 (-) putative cytochrome P450
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      • stPAI023
      		 15669 - 15902 (+)
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        • stPAI024
        • AAW49315.1
        		 16241 - 17005 (+) putative transposase
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          • stPAI025
          		 17118 - 17337 (-)
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            • stPAI026
            • AAW49316.1
            		 17498 - 18721 (+) putative transposase
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              • stPAI027
              • AAW49317.1
              		 19073 - 19711 (-) putative araC family regulatory protein
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                • pseudo21222_22427
                		 21223 - 22427 (+)
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                  • stPAI029
                  • AAW49318.1
                  • txtA
                  		 22745 - 27103 (+) thaxtomin synthetase A
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                    • stPAI030
                    • AAW49319.1
                    • txtB
                    		 27100 - 31617 (+) thaxtomin synthetase B
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                      • stPAI031
                      • AAW49320.1
                      • txtC
                      		 31971 - 33158 (+) cytochrome P450
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                        Biosynthesis information
                        Annotation changelog

                        Entry version: 4

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-10-07
                        Update chemical activity to schema version 2.11
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Removed annotation for irrelevant pseudogene
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Updated bioactivity data
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2019-10-16
                        Updated compound(s) information (NPAtlas curation)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2015-06-12
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        Detailed domain annotation
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