BGC0000470: bottromycin D biosynthetic gene cluster from Streptomyces sp. WMMB 272
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Location: 1 - 26,921 nt. (total: 26,921 nt).
This entry is originally from NCBI GenBank JX827389.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000470
Short description bottromycin D biosynthetic gene cluster from Streptomyces sp. WMMB 272
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Bottromycin)
Loci NCBI GenBank: JX827389.1
Compounds
  • bottromycin D
Species Streptomyces sp. WMMB 272 [taxonomy]
References
Chemical products information
bottromycin D
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C40H58N8O7S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFU90407.1
  • bstK
 12177 - 13436 (-) MFS-family/H+ antiporter
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  • AFU90406.1
  • bstB
 13697 - 14527 (-) O-methyltransferase
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  • AFU90405.1
  • bstC
 15052 - 17013 (+) radical SAM-dependent protein
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  • AFU90404.1
  • bstA
 17098 - 17238 (+) hypothetical protein
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  • AFU90403.1
  • bstD
 17302 - 18477 (+) YcaO protein
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  • AFU90402.1
  • bstE
 18395 - 19729 (+) YcaO protein
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  • AFU90401.1
  • bstF
 19726 - 21639 (+) radical SAM-dependent protein
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  • AFU90400.1
  • bstG
 21626 - 22468 (+) alpha-beta hydrolase
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  • AFU90399.1
  • bstH
 22586 - 23857 (+) amidohydrolase
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  • AFU90398.1
  • bstI
 23931 - 25070 (+) cytochrome P450
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  • AFU90397.1
  • bstJ
 25078 - >26921 (+) radical SAM-dependent protein
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RiPP-specific information
Subclass Bottromycin
Cyclic? no
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: SJG3CBEHSM6A3I74YXLH6GLA, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Changed subclass from cyanobactin to bottromycin
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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