BGC0000534 - 1 region(s) - antiSMASH results

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lanthipeptide-class-ii	1	6,359	High	mutacin K8	ribosomal:RiPP:Lanthipeptide

Gene/CDS overview

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Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 6,360
Label		BGC0000534

Tailoring functions

Lyases: cyclase

mukM: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000534.3	1.00	ribosomal	mutacin K8	Streptococcus mutans
BGC0000550.3	0.65	ribosomal	salivaricin G32	Streptococcus salivarius
BGC0000526.5	0.64	ribosomal	macedocin	Streptococcus macedonicus
BGC0001788.3	0.63	ribosomal	suicin 65	Streptococcus suis
BGC0000557.5	0.60	ribosomal	streptococcin A-FF22	Streptococcus pyogenes
BGC0000532.3	0.57	ribosomal	mutacin II	Streptococcus mutans
BGC0000521.3	0.56	ribosomal	lacticin 481	Lactococcus lactis subsp. lactis
BGC0000539.5	0.56	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0000547.5	0.54	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0000623.3	0.48	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000534.3	1.00	ribosomal	mutacin K8	Streptococcus mutans
BGC0000550.3	0.65	ribosomal	salivaricin G32	Streptococcus salivarius
BGC0000526.5	0.64	ribosomal	macedocin	Streptococcus macedonicus
BGC0001788.3	0.63	ribosomal	suicin 65	Streptococcus suis
BGC0000557.5	0.60	ribosomal	streptococcin A-FF22	Streptococcus pyogenes
BGC0000532.3	0.57	ribosomal	mutacin II	Streptococcus mutans
BGC0000521.3	0.56	ribosomal	lacticin 481	Lactococcus lactis subsp. lactis
BGC0000539.5	0.56	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0000547.5	0.54	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0000623.3	0.48	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum

Similar known clusters from MIBiG 4.0

Lanthipeptide predictions

Lanthipeptide(s) for mukM

mukA1

Leader:

MKNTTNEMLELIQEVSLDELDQVIGG

mukA3

Leader:

MKQSNEMLELIQEVSLDELDQVIGG

Shared core:

MGKGAVGTISHECRYNSWAFLATCCS

Core with dehydrations:

MGKGAVGDhbIDhaHECysRYNDhaWAFLADhbCysCysDha

antiSMASH-DB 4.0 matches for mukA1

100.0%

NC_013928.1and 8 others:

NC_013928.1 Lanthipeptides: SMUNN2025_RS01700_lanthipeptideNZ_CP023477.1 Lanthipeptides: CO204_RS01885_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01090_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01080_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01745_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01735_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07575_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07565_lanthipeptide

Lanthipeptides: SMUNN2025_RS01710_lanthipeptide

1

MGKGAVGTISHECRYNSWAFLATCCS

26

MGKGAVGTISHECRYNSWAFLATCCS

1

MGKGAVGTISHECRYNSWAFLATCCS

26

96.2%

NZ_CP023477.1:

Lanthipeptides: CO204_RS01875_lanthipeptide

1

MGKGAVGTISHECRYNSWAFLATCCS

26

MGKG VGTISHECRYNSWAFLATCCS

1

MGKGTVGTISHECRYNSWAFLATCCS

26

69.2%

NZ_CP018188.1and 17 others:

NZ_CP018188.1 Lanthipeptides: BSR19_RS11175_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07300_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07295_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09705_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09700_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05120_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05115_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04335_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04330_lanthipeptide

Lanthipeptides: BSR19_RS11180_lanthipeptide

2

GKGAVGTISHECRYNSWAFLATCCS

26

G G TISHEC N+WAFLATCCS

1

GNGVFKTISHECHLNTWAFLATCCS

25

with 67 more sequence matches

Only the first 10 are displayed here.

69.2%

NZ_VDNV01000006.1:

Lanthipeptides: FSV44_RS08765_lanthipeptide

2

GKGAVGTISHECRYNSWAFLATCCS

26

G G + TISHECR NSW FL TCCS

1

GGGVIQTISHECRMNSWQFLFTCCS

25

65.4%

NC_012470.1and 2 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06490_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09840_lanthipeptide

Lanthipeptides: SZO_RS04065_lanthipeptide

4

GAVGTISHECRYNSWAFLATCCS

26

GA+ TISHEC NSW FL TCCS

4

GAIKTISHECHMNSWQFLFTCCS

26

65.4%

NZ_ALSD01000046.1and 49 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08890_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02935_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08685_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08680_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05700_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08730_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08725_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08980_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08975_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01070_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09265_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09260_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08765_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08760_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08915_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08910_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02170_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09655_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03455_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03450_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08825_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08820_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03170_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08465_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09580_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09035_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09030_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08495_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08490_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08505_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08500_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06790_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06785_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04310_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04305_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02595_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02590_lanthipeptideNZ_CP035428.1 Lanthipeptides: ETT71_RS02815_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06680_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06675_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07265_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS105315_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03145_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03140_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06755_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06750_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS07040_lanthipeptide

Lanthipeptides: SAG0161_RS120605_lanthipeptide

3

KGAVGTISHECRYNSWAFLATCCS

26

G TISHEC N+WAFLATCCS

3

NGVFKTISHECHLNTWAFLATCCS

26

65.4%

NZ_CP023483.1:

Lanthipeptides: CNY62_RS11970_lanthipeptide

2

GKGAVGTISHECRYNSWAFLATCCS

26

G GA+ TISHEC N+W FL TCCS

1

GNGAIRTISHECHMNTWQFLFTCCS

25

65.4%

NZ_CP026729.1:

Lanthipeptides: BKKJ1_RS07010_lanthipeptide

2

GKGAVGTISHECRYNSWAFLATCC

25

G G V TISHEC NSW FL TCC

1

GNGVVTTISHECNMNSWQFLFTCC

24

65.4%

NZ_GL985606.1:

Lanthipeptides: HMPREF9062_RS00700_lanthipeptide

2

GKGAVGTISHECRYNSWAFLATCC

25

G G TISHEC YNSWAF+ TCC

1

GNGVFHTISHECYYNSWAFIFTCC

24

61.5%

NC_012470.1and 11 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06485_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05180_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09835_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09830_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05350_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05345_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05065_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05060_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05575_lanthipeptide

Lanthipeptides: SZO_RS04070_lanthipeptide

4

GAVGTISHECRYNSWAFLATCCS

26

G TISHEC NSW FL TCCS

4

GVFKTISHECHMNSWQFLFTCCS

26

61.5%

NZ_CAAHKQ010000003.1:

Lanthipeptides: E9664_RS02165_lanthipeptide

3

KGAVGTISHECRYNSWAFLATCCS

26

G TISHEC N+WAFLA CCS

3

NGVFKTISHECHLNTWAFLAICCS

26

61.5%

NZ_CP060646.1:

Lanthipeptides: H7789_RS06845_lanthipeptide

3

KGAVGTISHECRYNSWAFLATCCS

26

G TISHEC N+WA LATCCS

3

NGVFKTISHECHLNTWASLATCCS

26

61.5%

NZ_MSRJ01000005.1:

Lanthipeptides: BKH06_RS03755_lanthipeptide

3

KGAVGTISHECRYNSWAFLATCCS

26

+G V TISHEC NSW F+ TCCS

1

EGVVTTISHECNMNSWQFIFTCCS

24

MIBiG 4.0 matches for mukA1

21.4%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

2

GKGAVGTISHEC

13

KGA T++ EC

12

NKGAYCTLTVEC

23

12.8%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

8

TISHECRYN

16

T+S EC+ N

29

TLSKECQPN

37

mukA2

Leader:

MKQSDEMLELIQEVSLDELDQVIGG

Core:

AGNGVIRTITQGCRMPNNMQVLFTC

Core with dehydrations:

AGNGVIRDhbIDhbQGCysRMPNNMQVLFDhbCys

antiSMASH-DB 4.0 matches for mukA2

100.0%

NC_013928.1and 4 others:

NZ_CP023477.1 Lanthipeptides: CO204_RS01880_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01085_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01740_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07570_lanthipeptide

Lanthipeptides: SMUNN2025_RS01705_lanthipeptide

1

AGNGVIRTITQGCRMPNNMQVLFTC

25

AGNGVIRTITQGCRMPNNMQVLFTC

1

AGNGVIRTITQGCRMPNNMQVLFTC

25

60.0%

NZ_CP023483.1:

Lanthipeptides: CNY62_RS11970_lanthipeptide

2

GNGVIRTITQGCRMPNNMQVLFTC

25

GNG IRTI+ C M N Q LFTC

1

GNGAIRTISHECHM-NTWQFLFTC

23

60.0%

NZ_VDNV01000006.1:

Lanthipeptides: FSV44_RS08765_lanthipeptide

2

GNGVIRTITQGCRMPNNMQVLFTC

25

G GVI+TI+ CRM N+ Q LFTC

1

GGGVIQTISHECRM-NSWQFLFTC

23

with 45 more sequence matches

Only the first 10 are displayed here.

56.0%

NZ_CP026729.1:

Lanthipeptides: BKKJ1_RS07010_lanthipeptide

2

GNGVIRTITQGCRMPNNMQVLFTC

25

GNGV+ TI+ C M N+ Q LFTC

1

GNGVVTTISHECNM-NSWQFLFTC

23

56.0%

NZ_CP084014.1and 6 others:

NZ_CP084014.1 Lanthipeptides: LCQ72_RS00100_lanthipeptideNZ_CP084014.1 Lanthipeptides: LCQ72_RS00095_lanthipeptideNZ_CP094679.1 Lanthipeptides: K5I24_RS13105_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12415_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12410_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12405_lanthipeptide

Lanthipeptides: LCQ72_RS00105_lanthipeptide

2

GNGVIRTITQGCRMPNNMQVLFTC

25

GNGV++TI+ C M N Q LFTC

1

GNGVLKTISHECNM-NTWQFLFTC

23

56.0%

NZ_JAEEGA010000010.1:

Lanthipeptides: I6N95_RS15660_lanthipeptide

2

GNGVIRTITQGCRMPNNMQVLFTC

25

GNGVI+TI+ C M N+ Q +FTC

1

GNGVIKTISHECHM-NSWQWIFTC

23

56.0%

NZ_LT732526.1and 1 other:

NZ_LT732526.1 Lanthipeptides: BQ9856_RS23075_lanthipeptide

Lanthipeptides: BQ9856_RS23080_lanthipeptide

2

GNGVIRTITQGCRMPNNMQVLFTC

25

GNGVI+TI+ C M N Q +FTC

1

GNGVIKTISHECAM-NTWQFIFTC

23

52.0%

NZ_JH792236.1and 1 other:

NZ_JH792236.1 Lanthipeptides: IIM_RS26240_lanthipeptide

Lanthipeptides: IIM_RS26245_lanthipeptide

2

GNGVIRTITQGCRMPNNMQVLFTC

25

G+GVI+TI+ C M N+ Q +FTC

1

GSGVIKTISHECHM-NSWQAIFTC

23

52.0%

NZ_QTVL01000002.1and 5 others:

NZ_QTVL01000002.1 Lanthipeptides: DWZ44_RS04150_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14340_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14335_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02940_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02935_lanthipeptide

Lanthipeptides: DWZ44_RS04155_lanthipeptide

2

GNGVIRTITQGCRMPNNMQVLFTC

25

G+GV RTI+ C M N Q +FTC

1

GDGVFRTISHECNM-NTWQFIFTC

23

50.0%

NC_012470.1and 2 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06490_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09840_lanthipeptide

Lanthipeptides: SZO_RS04065_lanthipeptide

3

NGVIRTITQGCRMPNNMQVLFTC

25

NG I+TI+ C M N+ Q LFTC

3

NGAIKTISHECHM-NSWQFLFTC

24

50.0%

NC_012470.1and 11 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06485_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05180_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09835_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09830_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05350_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05345_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05065_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05060_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05575_lanthipeptide

Lanthipeptides: SZO_RS04070_lanthipeptide

3

NGVIRTITQGCRMPNNMQVLFTC

25

NGV +TI+ C M N+ Q LFTC

3

NGVFKTISHECHM-NSWQFLFTC

24

50.0%

NZ_MSRU01000008.1:

Lanthipeptides: BKH03_RS04355_lanthipeptide

1

AGNGVIRTITQGCRMPNNMQVLFTC

25

G+GV +IT C M N++QVL TC

1

GGDGVKWSITHECYM-NSLQVLLTC

24

48.1%

NZ_CP069183.1:

Lanthipeptides: LLNCDO700_RS13730_lanthipeptide

1

AGNGVIRTITQGCRMPNNMQVLFTC

25

G+GVI TI+ C M N+ Q +FTC

2

GGSGVIHTISHECNM-NSWQFVFTC

25

MIBiG 4.0 matches for mukA2

23.3%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

3

NGVIRTITQGCRMPN

17

NG T+T+ C+ PN

15

NGGWCTLTKECQ-PN

28

21.4%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

4

GVIRTITQGCRMPN

17

G T+T C MP+

14

GAYCTLTVEC-MPS

26

mukA_

Leader:

MKKGTQLYLEALEALQEIKVEELDTFIGG

Core:

GGRASNTISSDCRWNSLQAIFSCC

Core with dehydrations:

GGRADhaNDhbIDhaDhaDCysRWNDhaLQAIFDhaCysCys

antiSMASH-DB 4.0 matches for mukA_

100.0%

NC_013928.1and 4 others:

NZ_CP023477.1 Lanthipeptides: CO204_RS01890_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01095_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01750_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07560_lanthipeptide

Lanthipeptides: SMUNN2025_RS09965_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

GGRASNTISSDCRWNSLQAIFSCC

1

GGRASNTISSDCRWNSLQAIFSCC

24

75.0%

NZ_ALSD01000046.1and 5 others:

NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06795_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS10995_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS1000000113590_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03150_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS11590_lanthipeptide

Lanthipeptides: SAG0161_RS1000000124770_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

G NTIS++CRWNSLQAIFSCC

1

AGHGVNTISAECRWNSLQAIFSCC

24

75.0%

NZ_CAAHHE010000002.1and 13 others:

NZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08675_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05705_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08735_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08985_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01075_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09255_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08920_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09650_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03445_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03175_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02475_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09585_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08485_lanthipeptide

Lanthipeptides: E9499_RS02930_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

GG NTIS++CRWNSLQAIF+CC

1

GGHGVNTISAECRWNSLQAIFTCC

24

with 50 more sequence matches

Only the first 10 are displayed here.

70.8%

NC_012470.1and 15 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS10120_lanthipeptideNZ_CP018188.1 Lanthipeptides: BSR19_RS11185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05190_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07305_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09825_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05340_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09695_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10860_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05070_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04325_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05570_lanthipeptide

Lanthipeptides: SZO_RS10260_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

G NTIS++CRWNSLQAIF+CC

1

AGHGVNTISAECRWNSLQAIFTCC

24

70.8%

NZ_CAAHGW010000010.1and 12 others:

NZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08770_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02160_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08815_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08475_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09025_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08495_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02600_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06670_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07260_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06745_lanthipeptideNZ_NWMU01000024.1 Lanthipeptides: CO197_RS09155_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01580_lanthipeptide

Lanthipeptides: E9435_RS08895_lanthipeptide

2

GRASNTISSDCRWNSLQAIFSCC

24

G NTIS++CRWNSLQAIF+CC

2

GHGVNTISAECRWNSLQAIFTCC

24

52.0%

NZ_JH792236.1and 1 other:

NZ_JH792236.1 Lanthipeptides: IIM_RS26240_lanthipeptide

Lanthipeptides: IIM_RS26245_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

G TIS +C NS QAIF+CC

1

GSGVIKTISHECHMNSWQAIFTCC

24

52.0%

NZ_VDNV01000006.1:

Lanthipeptides: FSV44_RS08765_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

GG TIS +CR NS Q +F+CC

1

GGGVIQTISHECRMNSWQFLFTCC

24

48.0%

NZ_JAEEGA010000010.1:

Lanthipeptides: I6N95_RS15660_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

G TIS +C NS Q IF+CC

1

GNGVIKTISHECHMNSWQWIFTCC

24

45.8%

NZ_GL985606.1:

Lanthipeptides: HMPREF9062_RS00700_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

G +TIS +C +NS IF+CC

1

GNGVFHTISHECYYNSWAFIFTCC

24

45.8%

NZ_MSRJ01000005.1:

Lanthipeptides: BKH06_RS03755_lanthipeptide

7

TISSDCRWNSLQAIFSCC

24

TIS +C NS Q IF+CC

6

TISHECNMNSWQFIFTCC

23

45.8%

NZ_QTVL01000002.1and 5 others:

NZ_QTVL01000002.1 Lanthipeptides: DWZ44_RS04150_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14340_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14335_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02940_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02935_lanthipeptide

Lanthipeptides: DWZ44_RS04155_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

G TIS +C N+ Q IF+CC

1

GDGVFRTISHECNMNTWQFIFTCC

24

44.0%

NZ_CP023483.1:

Lanthipeptides: CNY62_RS11970_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

G A TIS +C N+ Q +F+CC

1

GNGAIRTISHECHMNTWQFLFTCC

24

44.0%

NZ_CP026729.1:

Lanthipeptides: BKKJ1_RS07010_lanthipeptide

1

GGRASNTISSDCRWNSLQAIFSCC

24

G TIS +C NS Q +F+CC

1

GNGVVTTISHECNMNSWQFLFTCC

24

MIBiG 4.0 matches for mukA_

20.8%

BGC0002111.3 (EVG22_32245):

Lanthipeptide: andalusicin A or andalusicin B

2

GRASNTISSDC

12

G ++TIS++C

13

GAWASTISNNC

23

20.8%

BGC0002111.3 (multiple genes):

Lanthipeptide: andalusicin A or andalusicin B

2

GRASNTISSDC

12

G ++TIS++C

13

GVWASTISNNC

23

10.3%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TISSDCRWN

15

T+S +C+ N

29

TLSKECQPN

37

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Identified secondary metabolite regions using strictness 'relaxed'

Legend:

Lanthipeptide(s) for mukM

antiSMASH-DB 4.0 matches for mukA1

MIBiG 4.0 matches for mukA1

antiSMASH-DB 4.0 matches for mukA2

MIBiG 4.0 matches for mukA2

antiSMASH-DB 4.0 matches for mukA_

MIBiG 4.0 matches for mukA_

Legend: