Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000534.1:
Cluster 1RiPP16359

BGC0000534, mutacin K8 biosynthetic gene cluster from Streptococcus mutans. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: mutacin K8

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
Lanthipeptide

Gene cluster description

mutacin K8 (BGC0000534). Gene Cluster 1. Biosynthetic class = RiPP. GenBank EF060238. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

mukA1 leader / core peptide, putative Class II
MKNTTNEMLELIQEVSLDELDQVIGG - MGKGAVGDhbIDhaHECRYNDhaWAFLADhbCCDha
mukA2 leader / core peptide, putative Class II
MKQSDEMLELIQEVSLDELDQVIGG - AGNGVIRDhbIDhbQGCRMPNNMQVLFDhbC
mukA3 leader / core peptide, putative Class II
MKQSNEMLELIQEVSLDELDQVIGG - MGKGAVGDhbIDhaHECRYNDhaWAFLADhbCCDha
mukA_ leader / core peptide, putative Class II
MKKGTQLYLEALEALQEIKVEELDTFIGG - GGRADhaNDhbIDhaDhaDCRWNDhaLQAIFDhaCC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Robson CL et al. (2007) Isolation and partial characterization of the Streptococcus mutans type AII lantibiotic mutacin K8. Microbiology 153(Pt 5):1631-41. doi: 10.1099/mic.0.2006/003756-0.