BGC0000547 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000547 (Streptococcus salivarius)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	lanthipeptide-class-ii	1	22,620	salivaricin 9	ribosomal:RiPP:Lanthipeptide	100%

BGC0000547 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 22,620 nt. (total: 22,620 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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Gene overview

MIBiG

MIBiG comparison

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 22,621
Label		BGC0000547

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000547	1.00	RiPP	salivaricin 9	Streptococcus salivarius
BGC0000499	0.38	RiPP	butyrivibriocin OR79	Butyrivibrio fibrisolvens
BGC0001210	0.37	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001787	0.37	RiPP	suicin 3908	Streptococcus suis
BGC0000626	0.36	RiPP	thuricin	Bacillus thuringiensis
BGC0000528	0.36	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000557	0.33	RiPP	streptococcin A-FF22	Streptococcus pyogenes
BGC0000561	0.32	RiPP	thermophilin 1277	Streptococcus thermophilus
BGC0000498	0.32	RiPP	bovicin HJ50	Streptococcus equinus
BGC0000532	0.32	RiPP	mutacin II	Streptococcus mutans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000547	1.00	RiPP	salivaricin 9	Streptococcus salivarius
BGC0000499	0.70	RiPP	butyrivibriocin OR79	Butyrivibrio fibrisolvens
BGC0001210	0.69	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001787	0.69	RiPP	suicin 3908	Streptococcus suis
BGC0000626	0.69	RiPP	thuricin	Bacillus thuringiensis
BGC0000528	0.68	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000557	0.66	RiPP	streptococcin A-FF22	Streptococcus pyogenes
BGC0000561	0.66	RiPP	thermophilin 1277	Streptococcus thermophilus
BGC0000498	0.66	RiPP	bovicin HJ50	Streptococcus equinus
BGC0000532	0.65	RiPP	mutacin II	Streptococcus mutans

Similar known gene clusters from MIBiG 4.0

Lanthipeptide predictions

Lanthipeptide(s) for sivM

sivA

Leader:

MKSTNNQSISEIAAVNSLQEVSMEELDQIIGA

Core:

GNGVVLTLTHECNLATWTKKLKCC

Core with dehydrations:

GNGVVLDhbLDhbHECysNLADhbWDhbKKLKCysCys

antiSMASH-DB 4.0 matches for sivA

100.0% NC_015760.1and 5 others:

NZ_CAJHJN010000010.1 Lanthipeptides: JMZ68_RS09030_lanthipeptideNZ_JACLQK010000036.1 Lanthipeptides: H7U04_RS11500_lanthipeptideNZ_JADPEB010000003.1 Lanthipeptides: I4U26_RS02800_lanthipeptideNZ_JAQCST010000021.1 Lanthipeptides: PGZ09_RS09470_lanthipeptideNZ_OU540596.1 Lanthipeptides: JQ838_RS05640_lanthipeptide

Lanthipeptides: SALIVB_RS03310_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

58.3% NZ_CP083176.1and 4 others:

NZ_JABUHD010000002.1 Lanthipeptides: HRR08_RS05415_lanthipeptideNZ_LSLF01000001.1 Lanthipeptides: AXE72_RS04025_lanthipeptideNZ_PNHB01000001.1 Lanthipeptides: CJ210_RS02800_lanthipeptideNZ_QJVA01000001.1 Lanthipeptides: D0T19_RS02755_lanthipeptide

Lanthipeptides: K9E37_RS06280_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GV+ TLTHEC++ TW L CC

GDGVMHTLTHECHMNTWQFLLTCC

54.2% NZ_CP084014.1and 6 others:

NZ_CP084014.1 Lanthipeptides: LCQ72_RS00100_lanthipeptideNZ_CP084014.1 Lanthipeptides: LCQ72_RS00095_lanthipeptideNZ_CP094679.1 Lanthipeptides: K5I24_RS13105_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12415_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12410_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12405_lanthipeptide

Lanthipeptides: LCQ72_RS00105_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGV+ T++HECN+ TW CC

GNGVLKTISHECNMNTWQFLFTCC

with 62 more sequence matches

52.0% NZ_CP018188.1and 17 others:

NZ_CP018188.1 Lanthipeptides: BSR19_RS11175_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07300_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07295_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09705_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09700_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05120_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05115_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04335_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04330_lanthipeptide

Lanthipeptides: BSR19_RS11180_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGV T++HEC+L TW CC

GNGVFKTISHECHLNTWAFLATCC

52.0% NZ_CP026729.1: Lanthipeptides: BKKJ1_RS07010_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGVV T++HECN+ +W CC

GNGVVTTISHECNMNSWQFLFTCC

50.0% NZ_AP025017.1: Lanthipeptides: MANAM107_RS05920_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

NGV+ T++HEC+L TW CC

NGVITTISHECHLNTWAFAFTCC

50.0% NZ_CP031746.1: Lanthipeptides: DCC27_RS08165_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

+GV+ TLTHEC++ +W L CC

DGVISTLTHECHMNSWQGLLTCC

50.0% NZ_CP072384.1: Lanthipeptides: J5A65_RS01395_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G GVV T+THEC++ +W CC

GRGVVPTVTHECHMNSWQWFFGCC

50.0% NZ_QTVL01000002.1and 5 others:

NZ_QTVL01000002.1 Lanthipeptides: DWZ44_RS04150_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14340_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14335_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02940_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02935_lanthipeptide

Lanthipeptides: DWZ44_RS04155_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GV T++HECN+ TW CC

GDGVFRTISHECNMNTWQFIFTCC

48.1% NZ_CP037940.1: Lanthipeptides: EQG49_RS07315_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GV+ TLTHEC + T+ L CC

GSGVIKTLTHECKMNTYQAILTCC

48.0% NZ_CP045267.1and 1 other:

NZ_CP045267.1 Lanthipeptides: FDZ14_RS00155_lanthipeptide

Lanthipeptides: FDZ14_RS00155_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GVV T T EC L T+ CC

GDGVVKTATSECYLGTFA--FACC

48.0% NZ_GL882519.1: Lanthipeptides: HMPREF9056_RS03330_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGV TL+HEC++ +W CC

GNGVYYTLSHECHMNSWQFIFTCC

48.0% NZ_LT732526.1and 1 other:

NZ_LT732526.1 Lanthipeptides: BQ9856_RS23075_lanthipeptide

Lanthipeptides: BQ9856_RS23080_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGV+ T++HEC + TW CC

GNGVIKTISHECAMNTWQFIFTCC

48.0% NZ_MSRJ01000005.1: Lanthipeptides: BKH06_RS03750_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGV T THECN ++ CC

GNGVFYTFTHECNTNSFYVAFTCC

46.2% NZ_ALSD01000046.1and 49 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08890_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02935_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08685_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08680_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05700_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08730_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08725_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08980_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08975_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01070_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09265_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09260_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08765_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08760_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08915_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08910_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02170_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09655_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03455_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03450_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08825_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08820_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03170_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08465_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09580_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09035_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09030_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08495_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08490_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08505_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08500_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06790_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06785_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04310_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04305_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02595_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02590_lanthipeptideNZ_CP035428.1 Lanthipeptides: ETT71_RS02815_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06680_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06675_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07265_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS105315_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03145_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03140_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06755_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06750_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS07040_lanthipeptide

Lanthipeptides: SAG0161_RS120605_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

NGV T++HEC+L TW CC

NGVFKTISHECHLNTWAFLATCC

46.2% NZ_CAAHKQ010000003.1: Lanthipeptides: E9664_RS02165_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

NGV T++HEC+L TW CC

NGVFKTISHECHLNTWAFLAICC

46.2% NZ_CP060646.1: Lanthipeptides: H7789_RS06845_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

NGV T++HEC+L TW CC

NGVFKTISHECHLNTWASLATCC

45.8% NZ_GL985606.1: Lanthipeptides: HMPREF9062_RS00700_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGV T++HEC +W CC

GNGVFHTISHECYYNSWAFIFTCC

45.8% NZ_MSRJ01000005.1: Lanthipeptides: BKH06_RS03755_lanthipeptide

GVVLTLTHECNLATWTKKLKCC

GVV T++HECN+ +W CC

GVVTTISHECNMNSWQFIFTCC

44.0% NZ_CP023483.1: Lanthipeptides: CNY62_RS11970_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNG + T++HEC++ TW CC

GNGAIRTISHECHMNTWQFLFTCC

44.0% NZ_FOZB01000002.1: Lanthipeptides: BM306_RS07850_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GV T++HEC++ TW CC

GDGVFRTISHECHMNTWMFIFTCC

44.0% NZ_JAEEGA010000010.1: Lanthipeptides: I6N95_RS15660_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGV+ T++HEC++ +W CC

GNGVIKTISHECHMNSWQWIFTCC

44.0% NZ_LR134406.1: Lanthipeptides: EL272_RS00695_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G G + + THECN T T+ CC

GWGSIFSFTHECNTNTMTQLFTCC

40.7% NZ_CP069183.1: Lanthipeptides: LLNCDO700_RS13730_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GV+ T++HECN+ +W CC

GSGVIHTISHECNMNSWQFVFTCC

40.0% NZ_JAFCGV010000005.1: Lanthipeptides: JQI09_RS04275_lanthipeptide

GNGVVLTLTHECNLATW

G+GVV T T EC L T+

GDGVVKTATSECYLGTF

40.0% NZ_JH792236.1and 1 other:

NZ_JH792236.1 Lanthipeptides: IIM_RS26240_lanthipeptide

Lanthipeptides: IIM_RS26245_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GV+ T++HEC++ +W CC

GSGVIKTISHECHMNSWQAIFTCC

40.0% NZ_VDNV01000006.1: Lanthipeptides: FSV44_RS08765_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G GV+ T++HEC + +W CC

GGGVIQTISHECRMNSWQFLFTCC

38.5% NC_012470.1and 11 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06485_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05180_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09835_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09830_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05350_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05345_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05065_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05060_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05575_lanthipeptide

Lanthipeptides: SZO_RS04070_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

NGV T++HEC++ +W CC

NGVFKTISHECHMNSWQFLFTCC

38.5% NC_013928.1and 8 others:

NC_013928.1 Lanthipeptides: SMUNN2025_RS01700_lanthipeptideNZ_CP023477.1 Lanthipeptides: CO204_RS01885_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01090_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01080_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01745_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01735_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07575_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07565_lanthipeptide

Lanthipeptides: SMUNN2025_RS01710_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G G V T++HEC +W CC

GKGAVGTISHECRYNSWAFLATCC

38.5% NZ_CP023477.1: Lanthipeptides: CO204_RS01875_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G G V T++HEC +W CC

GKGTVGTISHECRYNSWAFLATCC

38.5% NZ_CP117876.1: Lanthipeptides: PQ460_RS01735_lanthipeptide

GNGVVLTLTHECNLAT

G+GVV T T EC L T

GDGVVKTATSECYLGT

38.5% NZ_JAHBEV010000004.1and 3 others:

NZ_JAHBEX010000010.1 Lanthipeptides: KII86_RS06785_lanthipeptideNZ_JAHBFD010000039.1 Lanthipeptides: KIJ16_RS07340_lanthipeptideNZ_LN890331.1 Lanthipeptides: LEKG_RS02295_lanthipeptide

Lanthipeptides: KII98_RS01100_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

+GV+ T++HECN+ +W CC

SGVINTVSHECNMNSWQFVFTCC

38.5% NZ_MSRU01000008.1: Lanthipeptides: BKH03_RS04355_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GV ++THEC + + L CC

GDGVKWSITHECYMNSLQVLLTCC

37.5% NZ_CP046956.1: Lanthipeptides: ERJ70_RS03695_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

+G + T++HEC++ TW CC

DGAISTVSHECHMNTWQFIFTCC

37.0% NZ_CP046629.1and 3 others:

NZ_FNJX01000002.1 Lanthipeptides: BLR40_RS05025_lanthipeptideNZ_FNZS01000001.1 Lanthipeptides: BMX70_RS03125_lanthipeptideNZ_FOLK01000002.1 Lanthipeptides: BM262_RS05670_lanthipeptide

Lanthipeptides: GPA00_RS05740_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

G+GVV T++H+C++ +W CC

GSGVVPTVSHDCHMNSWQFLFTCC

37.0% NZ_CP114875.1: Lanthipeptides: O4Z47_RS14375_lanthipeptide

GNGVVLTLTHECN-LATW

+G + TLT EC+ LATW

SSGDICTLTSECDHLATW

36.0% NC_013928.1and 4 others:

NZ_CP023477.1 Lanthipeptides: CO204_RS01880_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01085_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01740_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07570_lanthipeptide

Lanthipeptides: SMUNN2025_RS01705_lanthipeptide

GNGVVLTLTHECNLATWTKKLKCC

GNGV+ T+T C + + L C

GNGVIRTITQGCRMPNNMQVLFTC

36.0% NZ_WBPF01000002.1: Lanthipeptides: F8162_RS00195_lanthipeptide

GVVLTLTHECNLATWTKKLKCC

G T++HEC+ TW CC

GQFDTISHECHWNTWQFLFTCC

34.6% NC_012470.1and 2 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06490_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09840_lanthipeptide

Lanthipeptides: SZO_RS04065_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

NG + T++HEC++ +W CC

NGAIKTISHECHMNSWQFLFTCC

34.6% NZ_NWMU01000024.1and 3 others:

NZ_NWMU01000024.1 Lanthipeptides: CO197_RS09145_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01575_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01570_lanthipeptide

Lanthipeptides: CO197_RS09150_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

NGV T++HEC++ ++ CC

NGVFKTISHECHMNSFQFFFTCC

33.3% NZ_CP044492.1and 1 other:

NZ_CP066294.2 Lanthipeptides: IGS65_RS08185_lanthipeptide

Lanthipeptides: FSA31_RS00605_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

GVV T+++EC + +W CC

QGVVPTVSYECRMNSWQHVFTCC

33.3% NZ_CP077726.1and 12 others:

NZ_CP077726.1 Lanthipeptides: KTC92_RS18420_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18415_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18410_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18405_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19070_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19065_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19060_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19055_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19050_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19045_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19040_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19035_lanthipeptide

Lanthipeptides: KTC92_RS18425_lanthipeptide

GNGVVLTLTHEC

GNGV+ T THEC

GNGVITTFTHEC

33.3% NZ_FNUH01000004.1and 1 other:

NZ_FOGM01000011.1 Lanthipeptides: BMX20_RS07220_lanthipeptide

Lanthipeptides: BLU50_RS05815_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

GVV T+++EC + +W CC

QGVVPTVSYECRMNSWQSIFTCC

31.0% NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21835_lanthipeptide

Lanthipeptides: CN325_RS21835_lanthipeptide

NGVVLTLTHECNLATW

+G V TLT EC A W

DGSVCTLTKECRPACW

30.8% NC_017912.1and 15 others:

NZ_BORO01000007.1 Lanthipeptides: KI343_RS07745_lanthipeptideNZ_CP007242.1 Lanthipeptides: KHU1_RS17410_lanthipeptideNZ_CP031424.1 Lanthipeptides: DXX91_RS18935_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS10440_lanthipeptideNZ_CP043809.1 Lanthipeptides: ETZ92_RS14260_lanthipeptideNZ_CP049904.1 Lanthipeptides: V753_RS18470_lanthipeptideNZ_CP053764.1 Lanthipeptides: HPQ66_RS18325_lanthipeptideNZ_CP061938.1 Lanthipeptides: IEN91_RS19800_lanthipeptideNZ_CP063768.1 Lanthipeptides: IM712_RS05205_lanthipeptideNZ_CP087137.1 Lanthipeptides: LOK79_RS18580_lanthipeptideNZ_CP092383.1 Lanthipeptides: MID02_RS19390_lanthipeptideNZ_JAEACM010000001.1 Lanthipeptides: I5F15_RS04355_lanthipeptideNZ_JAJNPN010000015.1 Lanthipeptides: LQ568_RS13285_lanthipeptideNZ_SDKF01000002.1 Lanthipeptides: EUA41_RS09950_lanthipeptideNZ_VDUT01000007.1 Lanthipeptides: FS412_RS14545_lanthipeptide

Lanthipeptides: MUS_RS20065_lanthipeptide

GNGVVLTLTHEC

G G V TLT EC

GGGGVCTLTSEC

30.0% NZ_CYXV01000003.1: Lanthipeptides: ARB75_RS04585_lanthipeptide

GVVLTLTHECNLATWTK

G+ TLT ECN+ T K

GIACTLTGECNIGTHIK

29.6% NZ_CP046304.1: Lanthipeptides: FOC54_RS00030_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

+GV+ T++H+C++ T+ CC

SGVIPTVSHDCHMNTFQFMFTCC

29.6% NZ_CP049223.1and 4 others:

NZ_CP049225.1 Lanthipeptides: G6Z85_RS06555_lanthipeptideNZ_CP049228.1 Lanthipeptides: G6Z83_RS06555_lanthipeptideNZ_JAKWZB010000003.1 Lanthipeptides: MMO78_RS01405_lanthipeptideNZ_PNGO01000002.1 Lanthipeptides: CJ224_RS02730_lanthipeptide

Lanthipeptides: G6Z86_RS06445_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

GV+ T++HEC + ++ CC

QGVLPTVSHECRMNSFQHIFTCC

29.6% NZ_CP071875.1: Lanthipeptides: J4I02_RS02880_lanthipeptide

NGVVLTLTHECNLATW

G + TLTHEC W

GGAICTLTHECAGTHW

29.6% NZ_CP086142.1and 3 others:

NZ_CP086142.1 Lanthipeptides: LL065_RS25460_lanthipeptideNZ_CP086142.1 Lanthipeptides: LL065_RS25455_lanthipeptideNZ_CP086142.1 Lanthipeptides: LL065_RS25450_lanthipeptide

Lanthipeptides: LL065_RS25465_lanthipeptide

GNGVVLTLTHEC

G GV+ T THEC

GGGVITTFTHEC

29.2% NZ_JALMDK010000017.1: Lanthipeptides: allorf_059288_059443_lanthipeptide

GVVLTLTHECN

G + TLT ECN

GYICTLTWECN

25.9% NZ_CP051645.1and 2 others:

NZ_JAKVFF010000018.1 Lanthipeptides: MKR34_RS11425_lanthipeptideNZ_VDOJ01000018.1 Lanthipeptides: FSV48_RS11975_lanthipeptide

Lanthipeptides: HHJ99_RS13350_lanthipeptide

NGVVLTLTHECNLATWTKKLKCC

+GV+ T++H+C++ ++ CC

SGVIPTVSHDCHMNSFQFVFTCC

25.8% NZ_CP095046.1: Lanthipeptides: MUN79_RS04140_lanthipeptide

GNGVVLTLTHECNLAT

G G+ LT++ ECN T

GPGMFLTISGECNGGT

25.0% NZ_BMMB01000007.1and 1 other:

NZ_BMMB01000007.1 Lanthipeptides: IEX62_RS15675_lanthipeptide

Lanthipeptides: IEX62_RS15680_lanthipeptide

GNGVVLTLTHEC

G+G + TLT +C

GDGWITTLTDDC

25.0% NZ_CP012649.1: Lanthipeptides: allorf_0469167_0469307_lanthipeptide

GNGVVLTLTH

G+GVVLT++

GDGVVLTVSD

23.5% NZ_WITJ01000001.1and 1 other:

NZ_WITJ01000001.1 Lanthipeptides: GHI93_RS00065_lanthipeptide

Lanthipeptides: GHI93_RS00065_lanthipeptide

NGVVLTLTHEC

NG V T THEC

NGYVCTWTHEC

23.3% NZ_CACZYW010000004.1and 1 other:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide

Lanthipeptides: HUF10_RS02825_lanthipeptide

NGVVLTLTHEC

NG TL+HEC

NGNWCTLSHEC

23.3% NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide

Lanthipeptides: allorf_0097945_0098112_lanthipeptide

GVVLTLTHEC

G TLTHEC

GYWCTLTHEC

23.3% NZ_CP040409.1and 4 others:

NZ_CP040414.1 Lanthipeptides: FE331_RS04030_lanthipeptideNZ_CP040415.1 Lanthipeptides: FE330_RS03440_lanthipeptideNZ_CP040417.1 Lanthipeptides: FE328_RS00755_lanthipeptideNZ_CP040424.1 Lanthipeptides: FE321_RS03455_lanthipeptide

Lanthipeptides: FE336_RS03460_lanthipeptide

GNGVVLTLTHEC

G G+V TLT +C

GPGLVRTLTKDC

23.3% NZ_CP051884.1and 2 others:

NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptideNZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide

Lanthipeptides: HGK68_RS15125_lanthipeptide

NGVVLTLTHEC

NG + T+THEC

NGWLCTITHEC

22.6% NZ_FNDV01000004.1: Lanthipeptides: BLR56_RS33870_lanthipeptide

GVVLTLTHECNLATWTKKLKCC

G NLA+W CC

GFSGIFDDPANLASWPTSTTCC

21.2% NC_017621.1and 16 others:

NZ_CP039462.1 Lanthipeptides: E8M06_RS05390_lanthipeptideNZ_JABTZM010000032.1 Lanthipeptides: HRQ47_RS09675_lanthipeptideNZ_JAEVFQ010000010.1 Lanthipeptides: JNO64_RS06375_lanthipeptideNZ_JAFFHD010000003.1 Lanthipeptides: JN532_RS02075_lanthipeptideNZ_JAGFVG010000007.1 Lanthipeptides: J5581_RS04225_lanthipeptideNZ_JAIJZO010000001.1 Lanthipeptides: K5Q34_RS00965_lanthipeptideNZ_JAIMDS010000024.1 Lanthipeptides: K6V32_RS10650_lanthipeptideNZ_JAJUWV010000001.1 Lanthipeptides: LZF89_RS05505_lanthipeptideNZ_JAMDIS010000017.1 Lanthipeptides: M5P45_RS08180_lanthipeptideNZ_JAMYIU010000001.1 Lanthipeptides: NKE44_RS01780_lanthipeptideNZ_JAMYIX010000001.1 Lanthipeptides: NKE54_RS02675_lanthipeptideNZ_JAMYIY010000001.1 Lanthipeptides: NKE64_RS02785_lanthipeptideNZ_JAMYJP010000014.1 Lanthipeptides: NKE68_RS07350_lanthipeptideNZ_LR738722.1 Lanthipeptides: STREPSUIS_RS03955_lanthipeptideNZ_VZMP01000023.1 Lanthipeptides: F6P50_RS09295_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05700_lanthipeptide

Lanthipeptides: SSUD12_RS06540_lanthipeptide

GNGVVLTLTHEC

G+G V TLT +C

GSGFVKTLTKDC

21.2% NZ_AQQB01000068.1and 6 others:

NZ_BCEY01000024.1 Lanthipeptides: GOZ53_RS05100_lanthipeptideNZ_BCEZ01000067.1 Lanthipeptides: GOZ55_RS11230_lanthipeptideNZ_BCFC01000053.1 Lanthipeptides: GOZ35_RS07920_lanthipeptideNZ_BCFG01000017.1 Lanthipeptides: GOZ50_RS03220_lanthipeptideNZ_BCFI01000009.1 Lanthipeptides: GOZ54_RS02495_lanthipeptideNZ_CP019557.1 Lanthipeptides: BZG42_RS05725_lanthipeptide

Lanthipeptides: K738_RS01000000110290_lanthipeptide

GNGVVLTLTHEC

G+G+V TLT +C

GSGLVKTLTKDC

19.4% NZ_CP034248.1: Lanthipeptides: EIM92_RS14995_lanthipeptide

GVVLTLTHECNL

GV+ T++HEC+

GVICTISHECHY

19.4% NZ_CP102975.1and 1 other:

NZ_FMOE01000002.1 Lanthipeptides: BJT27_RS07805_lanthipeptide

Lanthipeptides: NW953_RS00170_lanthipeptide

NGVVLTLTHEC

NG + T++HEC

NGKLCTVSHEC

MIBiG 3.1 matches for sivA

23.3% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

NGVVLTLTHEC

NG TLT EC

NGGWCTLTKEC

21.4% BGC0000517 (BAB04173.1): Lanthipeptide: haloduracin β or haloduracin α

GVVLTLTHEC

G TLT EC

GAYCTLTVEC

allorf_08465_08653

Leader:

MSPNSPITLVAVVSA

Core:

IPGIERRISYSGRGLANSTNCSKTCSRRFVNLISSCALYWLFVNCSG

Core with dehydrations:

IPGIERRIDhaYDhaGRGLANDhaDhbNCysDhaKDhbCysDhaRRFVNLIDhaDhaCysALYWLFVNCysDhaG

antiSMASH-DB 4.0 matches for allorf_08465_08653

19.1% NC_013947.1: Lanthipeptides: SNAS_RS17185_lanthipeptide

ERRISYSGRGLANSTNCSK

E R Y A STNC+K

ELRELYIHEATAQSTNCTK

14.0% NZ_JADWPD010000048.1: Lanthipeptides: I4Q55_RS46280_lanthipeptide

RGLANSTNCSKTCSRRFV

G ++NC+ TC RF

EGCTTTSNCTITCYTRFA

allorf_08730_08867

Leader:

MSFAFLIEICDMARIGM

Core:

ASCSDIVNTFVQNFSCIRIPTLSDMLLT

Core with dehydrations:

ADhaCysDhaDIVNDhbFVQNFDhaCysIRIPDhbLDhaDMLLDhb

antiSMASH-DB 4.0 matches for allorf_08730_08867

28.6% NZ_CP085297.1: Lanthipeptides: allorf_03653_03829_lanthipeptide

NFSCIRIPTLSDMLL

+F CI+I L MLL

SFKCIKISPLWLMLL

21.4% NZ_CP040938.1: Lanthipeptides: allorf_0462507_0462617_lanthipeptide

NTFVQNFSCIR

N +QN SC+R

NKHLQNNSCLR

14.3% NZ_CP096019.1: Lanthipeptides: allorf_1451265_1451483_lanthipeptide

NTFVQNFSCIRIP

+++ + SC+R P

SSYAEEVSCLRTP

MIBiG 3.1 matches for allorf_08730_08867

21.4% BGC0000503 (cinA): Lanthipeptide: cinnamycin

SCSDIVNTFV

SCS TFV

SCSFGPFTFV

21.4% BGC0000563 (AEA03263.1): Lanthipeptide: venezuelin

ASCSDIVNTFVQNFSCIRI

A+C + + N CI I

ATCECVGLLTLLNTVCIGI

14.3% BGC0000563 (AEA03263.1): Lanthipeptide: venezuelin

IVNTFVQNFSC

++NT SC

LLNTVCIGISC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

sivA - Class II

Cleavage pHMM score: 5.20

RODEO score: 0

Monoisotopic mass: 2559.3 Da

Molecular weight: 2561.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2579.1 Da N = 1

allorf_08465_08653 - Class II

Cleavage pHMM score: -6.90

RODEO score: 0

Monoisotopic mass: 5018.6 Da

Molecular weight: 5021.7 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 5039.8 Da N = 1; 5057.8 Da N = 2; 5075.8 Da N = 3; 5093.8 Da N = 4; 5111.8 Da N = 5; 5129.9 Da N = 6

allorf_08730_08867 - Class II

Cleavage pHMM score: -7.30

RODEO score: 0

Monoisotopic mass: 2961.5 Da

Molecular weight: 2963.4 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2981.4 Da N = 1; 2999.5 Da N = 2; 3017.5 Da N = 3; 3035.5 Da N = 4; 3053.5 Da N = 5