Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000549.1:
Cluster 1RiPP115313

BGC0000549, salivaricin D biosynthetic gene cluster from Streptococcus salivarius. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: salivaricin D

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
Lanthipeptide

Gene cluster description

salivaricin D (BGC0000549). Gene Cluster 1. Biosynthetic class = RiPP. GenBank JN564797, positions 22603-37915. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

slvN leader / core peptide, putative Class I
MATKDFNLDLVEVSKSNTGASTR - IDhbDhaHDhaFCDhaQACKDhbYKILGCNLLDhbHGCRFPR
slvD leader / core peptide, putative Class I
MSTKDFNLDLVEVSKSNTGASAR - FDhbDhaHDhaLCDhbPGCIDhbGVLMGCHIQDhaIGCNVHIHIDhaK

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Birri DJ et al. (2012) Salivaricin D, a novel intrinsically trypsin-resistant lantibiotic from Streptococcus salivarius 5M6c isolated from a healthy infant. Appl Environ Microbiol 78(2):402-10. doi: 10.1128/AEM.06588-11. Epub