Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000552.1:
Cluster 1RiPP111776

BGC0000552, Smb A / Smb B biosynthetic gene cluster from Streptococcus mutans. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: Smb A

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
Lanthipeptide

Gene cluster description

Smb A / Smb B (BGC0000552). Gene Cluster 1. Biosynthetic class = RiPP. GenBank AB179778. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

smbA leader / core peptide, putative Class II
MKSNLLKINNVTEMEKNMVTLIKDEDMLAG - GDhaDhbPACAIGVVGIDhbVAVDhbGIDhaDhbACDhbDhaRCINK
smbB leader / core peptide, putative Class II
MKEIQKAGLQEELSILMDDANNLEQLTAG - IGDhbDhbVVNDhaDhbFDhaIVLGNKGYICDhbVDhbVECMRNCDhaK

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Yonezawa H, Kuramitsu HK. (2005) Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5. Antimicrob Agents Chemother 49(2):541-8. doi: