BGC0000581: microcin J25 biosynthetic gene cluster from Escherichia coli AY25
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Location: 1 - 4,496 nt. (total: 4,496 nt).
This entry is originally from NCBI GenBank AF061787.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000581
Short description microcin J25 biosynthetic gene cluster from Escherichia coli AY25
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Remarks "BGC was originally isolated from a plasmid: see DOI: 10.1128/jb.181.8.2659-2662.1999"
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
AF061787.1
1 - 4496
via Heterologous expression
Compounds
  • microcin J25
Species Escherichia coli AY25 [taxonomy]
References
Chemical products information
microcin J25 Evidence:
Copy SMILES
C101H139N23O27
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAD28494.1
  • mcjA
 62 - 238 (-) RiPP precursor peptide
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    • AAD28495.1
    • mcjB
    		 578 - 1204 (+) McjB
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      • AAD28496.1
      • mcjC
      		 1207 - 2535 (+) McjC
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        • AAD28497.1
        • mcjD
        		 2754 - 4496 (+) McjD
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          Biosynthesis information
          Annotation changelog

          Entry version: next

          Date
          Changes
          Submitters
          Reviewers
          2024-07-23
          MIBiG v4 annotathon
          • (ID: G42B4RI57WLTDHDCD4PMU3MJ)
          • (ID: C62OJVVH7XOTOTFZSJT727YU)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: next

          Date
          Changes
          Submitters
          Reviewers
          2023-10-18
          Added locus coordinates, evidence, completeness, bioactivity, precursor peptide-gene information. Changed PubMed IDs to DOIs, changed subclass to 'Lassopeptide'. Corrected SMILES structure. Added gene product annotation. Added correct strain identifier.
          • (ID: C62OJVVH7XOTOTFZSJT727YU)
          • (ID: RKFOW2BJ2UIGZ6GYHFZX4BHF)

          Entry version: 4

          Date
          Changes
          Submitters
          Reviewers
          2022-10-07
          Update chemical activity to schema version 2.11
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          2022-09-15
          Updated bioactivity data
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          2019-10-16
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2019-10-16
          Updated compound(s) information (NPAtlas curation)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          2015-06-12
          Submitted
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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