BGC0000606: lactazole biosynthetic gene cluster from Streptomyces lactacystinaeus
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Location: 1 - 14,244 nt. (total: 14,244 nt).
This entry is originally from NCBI GenBank AB820694.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000606
Short description lactazole biosynthetic gene cluster from Streptomyces lactacystinaeus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Thiopeptide)
Loci NCBI GenBank: AB820694.1
Compounds
  • lactazole
Species Streptomyces lactacystinaeus [taxonomy]
References
Chemical products information
lactazole
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAO57433.1
  • ltc74
 1 - 2574 (+) serine/threonine protein kinase
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  • BAO57434.1
  • lazA
 2976 - 3149 (+) lactazole precursor peptide
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  • BAO57435.1
  • lazB
 3371 - 6013 (+) lantibiotic-type dehydratase
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  • BAO57436.1
  • lazC
 6006 - 7226 (+) lantibiotic-type dehydratase
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  • BAO57437.1
  • lazD
 7223 - 8920 (+) hypothetical protein
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  • BAO57438.1
  • lazE
 8917 - 10983 (+) cyclodehydratase
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  • BAO57439.1
  • lazF
 11064 - 12737 (+) dehydrogenase
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  • BAO57440.1
  • ltc66
 12981 - 13334 (-) peptidase
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  • BAO57441.1
  • ltc65
 13417 - 14244 (-) creatininase
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RiPP-specific information
Subclass Thiopeptide
Cyclic? no
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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