BGC0000614: thiostrepton biosynthetic gene cluster from Streptomyces laurentii
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Location: 1 - 29,379 nt. (total: 29,379 nt).
This entry is originally from NCBI GenBank FJ652572.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000614
Short description thiostrepton biosynthetic gene cluster from Streptomyces laurentii
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Thiopeptide)
Loci NCBI GenBank: FJ652572.1
Compounds
  • thiostrepton
Species Streptomyces laurentii [taxonomy]
References
Chemical products information
thiostrepton
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C72H85N19O18S5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACN52311.1
 16 - 1104 (-) TsrV
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  • ACN52310.1
 1126 - 1956 (-) TsrU
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  • ACN52309.1
 2015 - 3871 (-) TsrT
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  • ACN52308.1
 4011 - 4418 (-) TsrS
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  • ACN52307.1
 4493 - 5722 (-) TsrQ
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  • ACN52306.1
 5924 - 6859 (-) TsrP
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  • ACN52305.1
 6930 - 7481 (-) TsrO
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  • ACN52291.1
 7900 - 8076 (+) TsrA
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  • ACN52292.1
 8593 - 9384 (+) TsrB
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  • ACN52293.1
 9377 - 12178 (+) TsrC
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  • ACN52294.1
 12175 - 13215 (+) TsrD
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  • ACN52295.1
 13202 - 14308 (+) TsrE
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  • ACN52296.1
 14305 - 16074 (+) TsrF
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  • ACN52297.1
 16071 - 17909 (+) TsrG
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  • ACN52298.1
 17906 - 19951 (+) TsrH
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  • ACN52299.1
 19929 - 21353 (+) TsrI
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  • ACN52300.1
 21329 - 22642 (+) TsrJ
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  • ACN52301.1
 22752 - 23942 (+) TsrK
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  • ACN52302.1
 24005 - 26743 (+) TsrL
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  • ACN52303.1
 26760 - 28559 (+) TsrM
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  • ACN52304.1
 28556 - 29374 (+) TsrN
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RiPP-specific information
Subclass Thiopeptide
Cyclic? no
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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