BGC0000615: TP-1161 biosynthetic gene cluster from Nocardiopsis sp. TFS65-07
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Location: 1 - 35,080 nt. (total: 35,080 nt).
This entry is originally from NCBI GenBank HM467197.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000615
Short description TP-1161 biosynthetic gene cluster from Nocardiopsis sp. TFS65-07
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
HM467197.1
via Knock-out studies
Compounds
  • TP-1161
Species Nocardiopsis sp. TFS65-07 [taxonomy]
References
Chemical products information
TP-1161 Evidence:
Copy SMILES
C50H47N15O13S3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADO67763.1
  • tpa1
 1 - 429 (+) tpa1
  • Resistance/immunity
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  • ADO67764.1
  • tpa2
 518 - 1195 (+) tpa2
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    • ADO67765.1
    • tpa3
    		 1603 - 2130 (+) tpa3
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      • ADO67766.1
      • tpa4
      		 2227 - 2616 (+) tpa4
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        • ADO67767.1
        • tpa5
        		 3355 - 6822 (+) tpa5
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          • ADO67768.1
          • tpa6
          		 6857 - 10735 (+) tpa6
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            • ADO67769.1
            • tpa7
            		 10852 - 14034 (+) hypothetical protein
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              • ADO67770.1
              • tpaA
              		 14405 - 14551 (+) tpaA
              • Scaffold biosynthesis
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              • ADO67771.1
              • tpaB
              		 14689 - 15756 (+) hypothetical protein
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                • ADO67772.1
                • tpaC
                		 15806 - 17152 (+) tpaC
                • Scaffold biosynthesis
                • Knock-out
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                • ADO67773.1
                • tpaD
                		 17180 - 17782 (+) tpaD
                • Scaffold biosynthesis
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                • ADO67774.1
                • tpaE
                		 17794 - 19434 (+) tpaE
                • Scaffold biosynthesis
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                • ADO67775.1
                • tpaF
                		 19424 - 20125 (+) tpaF
                • Scaffold biosynthesis
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                • ADO67776.1
                • tpaG
                		 20217 - 22031 (+) hypothetical protein
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                  • ADO67777.1
                  • tpaH
                  		 22028 - 23893 (+) tpaH
                  • Scaffold biosynthesis
                  • Knock-out
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                  • ADO67778.1
                  • tpaI
                  		 24008 - 24817 (-) tpaI
                  • Resistance/immunity
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                  • ADO67779.1
                  • tpaJ
                  		 24879 - 26093 (-) tpaJ
                  • Activation / processing
                  • Knock-out
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                  • ADO67780.1
                  • tpaX
                  		 26463 - 26609 (+) tpaX
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                    • ADO67781.1
                    • tpaK
                    		 26673 - 29462 (+) tpaK
                    • Activation / processing
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                    • ADO67782.1
                    • tpaL
                    		 29497 - 30369 (+) tpaL
                    • Activation / processing
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                    • ADO67783.1
                    • tpa8
                    		 30799 - 31170 (+) tpa8
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                      • ADO67784.1
                      • tpa9
                      		 31173 - 31643 (+) tpa9
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                        • ADO67785.1
                        • tpa10
                        		 31692 - 33803 (+) tpa10
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                          • ADO67786.1
                          • tpa11
                          		 33887 - 35080 (+) tpa11
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                            Biosynthesis information
                            Annotation changelog

                            Entry version: 3

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2022-10-07
                            Update chemical activity to schema version 2.11
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 2

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2019-10-16
                            Migrated from v1.4
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            2019-10-16
                            Updated compound(s) information (MIBiG Annotathon)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            2019-10-16
                            Updated compound(s) information (NPAtlas curation)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                            Entry version: 1

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2015-06-12
                            Submitted
                            • (ID: MU4LZLKCEF7Q67JF6ZEMKX3R)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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