BGC0000615: TP-1161 biosynthetic gene cluster from Nocardiopsis sp. TFS65-07
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 35,080 nt. (total: 35,080 nt).
This entry is originally from NCBI GenBank HM467197.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000615
Short description TP-1161 biosynthetic gene cluster from Nocardiopsis sp. TFS65-07
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Thiopeptide)
Loci NCBI GenBank: HM467197.1
Compounds
  • TP-1161
Species Nocardiopsis sp. TFS65-07 [taxonomy]
References
Chemical products information
TP-1161
Copy SMILES
C50H47N15O13S3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADO67763.1
  • tpa1
 1 - 429 (+) tpa1
  • Resistance/immunity
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67764.1
  • tpa2
 518 - 1195 (+) tpa2
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67765.1
  • tpa3
 1603 - 2130 (+) tpa3
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67766.1
  • tpa4
 2227 - 2616 (+) tpa4
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67767.1
  • tpa5
 3355 - 6822 (+) tpa5
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67768.1
  • tpa6
 6857 - 10735 (+) tpa6
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67769.1
  • tpa7
 10852 - 14034 (+) hypothetical protein
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67770.1
  • tpaA
 14405 - 14551 (+) tpaA
  • Scaffold biosynthesis
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67771.1
  • tpaB
 14689 - 15756 (+) hypothetical protein
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67772.1
  • tpaC
 15806 - 17152 (+) tpaC
  • Scaffold biosynthesis
Knock-out
copy AA seq
copy Nt seq
  • ADO67773.1
  • tpaD
 17180 - 17782 (+) tpaD
  • Scaffold biosynthesis
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67774.1
  • tpaE
 17794 - 19434 (+) tpaE
  • Scaffold biosynthesis
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67775.1
  • tpaF
 19424 - 20125 (+) tpaF
  • Scaffold biosynthesis
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67776.1
  • tpaG
 20217 - 22031 (+) hypothetical protein
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67777.1
  • tpaH
 22028 - 23893 (+) tpaH
  • Scaffold biosynthesis
Knock-out
copy AA seq
copy Nt seq
  • ADO67778.1
  • tpaI
 24008 - 24817 (-) tpaI
  • Resistance/immunity
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67779.1
  • tpaJ
 24879 - 26093 (-) tpaJ
  • Activation / processing
Knock-out
copy AA seq
copy Nt seq
  • ADO67780.1
  • tpaX
 26463 - 26609 (+) tpaX
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67781.1
  • tpaK
 26673 - 29462 (+) tpaK
  • Activation / processing
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67782.1
  • tpaL
 29497 - 30369 (+) tpaL
  • Activation / processing
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67783.1
  • tpa8
 30799 - 31170 (+) tpa8
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67784.1
  • tpa9
 31173 - 31643 (+) tpa9
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67785.1
  • tpa10
 31692 - 33803 (+) tpa10
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
  • ADO67786.1
  • tpa11
 33887 - 35080 (+) tpa11
  • Unknown
Sequence-based prediction
copy AA seq
copy Nt seq
RiPP-specific information
Subclass Thiopeptide
Cyclic? yes
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: MU4LZLKCEF7Q67JF6ZEMKX3R, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.