BGC0000628: lactocillin biosynthetic gene cluster from Lactobacillus paragasseri JV-V03
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Location: 9,724 - 23,523 nt. (total: 13,800 nt).
This entry is originally from NCBI GenBank ACGO02000004.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000628
Short description lactocillin biosynthetic gene cluster from Lactobacillus paragasseri JV-V03
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
ACGO02000004.1
9724 - 23523
via Knock-out studies
Compounds
  • lactocillin
Species Lactobacillus paragasseri JV-V03 [taxonomy]
References
Chemical products information
lactocillin Evidence:
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C51H45N13O10S7
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • HMPREF0514_11727
  • EFJ68960.1
 9724 - 10086 (+) hypothetical protein
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    • HMPREF0514_11728
    • EFJ68961.1
    • frr2
    		 10223 - 10399 (+) thiazolylpeptide-type bacteriocin precursor
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      • HMPREF0514_11729
      • EFJ68962.1
      		 10567 - 11256 (+) hypothetical protein
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        • HMPREF0514_11730
        • EFJ68963.1
        		 11273 - 13030 (+) YcaO-like family
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          • HMPREF0514_11731
          • EFJ68964.1
          		 13099 - 15633 (+) lantibiotic dehydratase domain protein
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            • HMPREF0514_11732
            • EFJ68965.1
            		 15623 - 16465 (+) thiopeptide-type bacteriocin biosynthesis domain protein
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              • HMPREF0514_11733
              • EFJ68966.1
              		 16452 - 17237 (+) hypothetical protein
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                • HMPREF0514_11734
                • EFJ68967.1
                		 17242 - 18609 (+) hypothetical protein
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                  • HMPREF0514_11735
                  • EFJ68968.1
                  		 18611 - 18820 (+) hypothetical protein
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                    • HMPREF0514_11736
                    • EFJ68969.1
                    • acsA-1
                    		 18807 - 20279 (+) AMP-binding enzyme
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                      • HMPREF0514_11737
                      • EFJ68970.1
                      		 20281 - 21168 (+) hydrolase, alpha/beta domain protein
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                        • HMPREF0514_11738
                        • EFJ68971.1
                        		 21137 - 21598 (+) TipAS antibiotic-recognition domain protein
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                          • HMPREF0514_11739
                          • EFJ68972.1
                          		 21606 - 22493 (+) ATPase, AAA family
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                            • HMPREF0514_11740
                            • EFJ68973.1
                            		 22912 - 23523 (+) site-specific recombinase, phage integrase family
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                              Biosynthesis information
                              Annotation changelog

                              Entry version: 3

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-10-07
                              Update chemical activity to schema version 2.11
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 2

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2019-10-16
                              Migrated from v1.4
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2015-06-12
                              Submitted
                              • (ID: OVR6EKPL57AJOPBA4Z45OQI7)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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