BGC0000652: napyradiomycin biosynthetic gene cluster from Streptomyces sp. CNQ525
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Location: 1 - 36,405 nt. (total: 36,405 nt).
This entry is originally from NCBI GenBank EF397639.1.

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core biosynthetic genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000652
Short description napyradiomycin biosynthetic gene cluster from Streptomyces sp. CNQ525
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Unknown)
Loci
EF397639.1
via
Compounds
  • napyradiomycin
Species Streptomyces sp. CNQ525 [taxonomy]
References
Chemical products information
napyradiomycin Evidence: NMR [1]
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C25H30Cl2O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABS50474.1
  • napT5
 1 - 674 (-) putative mevalonate decarboxylase
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    • ABS50475.1
    • napT6
    		 682 - 1665 (-) putative mevalonate kinase
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      • ABS50476.1
      • napU1
      		 2557 - 3234 (-) NapU1
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        • ABS50477.1
        • napU2
        		 3474 - 4241 (+) NapU2
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          • ABS50478.1
          • napB1
          		 4315 - 5382 (+) putative THNS
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            • ABS50479.1
            • napB2
            		 5453 - 6010 (+) putative monooxygenase
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              • ABS50480.1
              • napB3
              		 5742 - 7181 (+) putative pyridoxal phosphate
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                • ABS50481.1
                • napB4
                		 7368 - 8957 (+) putative acyl-CoA synthase
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                  • ABS50482.1
                  • napT7
                  		 9052 - 10125 (+) putative polyprenyl synthase
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                    • ABS50483.1
                    • napR1
                    		 10433 - 11239 (+) putative regulatory protein
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                      • ABS50484.1
                      • napR2
                      		 11340 - 12611 (+) putative sodium transporter
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                        • ABS50485.1
                        • napR3
                        		 12749 - 13411 (+) putative transcription regulator
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                          • ABS50486.1
                          • napH1
                          		 13560 - 15143 (-) putative vanadium chloroperoxidase
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                            • ABS50487.1
                            • napU3
                            		 15698 - 16318 (+) hypothetical protein
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                              • ABS50488.1
                              • napH2
                              		 16667 - 17944 (+) putative FADH2 dependent halogenase
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                                • ABS50489.1
                                • napT8
                                		 19734 - 20627 (-) putative prenyltransferase
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                                  • ABS50490.1
                                  		 20916 - 21836 (+) putative prenyltransferase
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                                    • ABS50491.1
                                    • napH3
                                    		 21944 - 23269 (+) putative vanadium chloroperoxidase
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                                      • ABS50492.1
                                      • napH4
                                      		 23830 - 25020 (+) putative vanadium chloroperoxidase
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                                        • ABS50493.1
                                        • napB5
                                        		 25504 - 26538 (+) putative methyltransferase
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                                          • ABS50494.1
                                          • napR4
                                          		 26868 - 28262 (+) putative transporter
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                                            • ABS50495.1
                                            • napR5
                                            		 28728 - 30335 (+) putative efflux protein
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                                              • ABS50496.1
                                              • napR6
                                              		 30663 - 32270 (+) putative efflux protein
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                                                • ABS50497.1
                                                • napR7
                                                		 32267 - 32926 (+) putative transcription regulator
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                                                  • ABS50498.1
                                                  • napR8
                                                  		 34017 - 34952 (-) putative regulatory protein
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                                                    • ABS50499.1
                                                    • napU4
                                                    		 35111 - 35797 (-) hypothetical protein
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                                                      Biosynthesis information
                                                      Annotation changelog

                                                      Entry version: next

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      2024-05-14
                                                      MIBiG v4 annotathon
                                                      • (ID: NHJ6M55E7ZEHUFNMEG4QIZWY)
                                                      • (ID: 4ZBJCWV5NZUBDJXCSIV4TKIA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 4

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      2022-10-07
                                                      Update chemical activity to schema version 2.11
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 3

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      2022-09-15
                                                      Updated bioactivity data
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 2

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      2019-10-16
                                                      Migrated from v1.4
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 1

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      2015-06-12
                                                      Submitted
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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