BGC0000684 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000684 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	21,746	TAN-1612 / 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione / desmethyl TAN-1612	Polyketide:Iterative type I	60%

BGC0000684 - Region 1 - T1PKS

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Location: 1 - 21,746 nt. (total: 21,746 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 21,747
Label		BGC0000684

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000684.1	0.67	Terpene	asperthecin	Aspergillus nidulans FGSC A4
BGC0000156.1	0.28	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0000013.1	0.27	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001858.1	0.25	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.23	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001284.1	0.23	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001909.1	0.23	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001265.1	0.23	Polyketide	melanin	Bipolaris oryzae
BGC0001258.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000684.1	0.87	Terpene	asperthecin	Aspergillus nidulans FGSC A4
BGC0000156.1	0.62	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0000013.1	0.60	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001858.1	0.58	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.57	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001284.1	0.56	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001909.1	0.56	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001265.1	0.56	Polyketide	melanin	Bipolaris oryzae
BGC0001258.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 21746:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ANIA_06000

PKS_AT (928..1223): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 58.3%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 85.5
Methylmalonyl-CoA: 62.3
Methoxymalonyl-CoA: 57.9
inactive: 44.4
Isobutyryl-CoA: 27.7
Benzoyl-CoA: 26.8
Propionyl-CoA: 25.4
Acetyl-CoA: 22.5
2-Methylbutyryl-CoA: 21.7
fatty_acid: 20.8
Ethylmalonyl-CoA: 15.8
CHC-CoA: 14.6
3-Methylbutyryl-CoA: 12.5
trans-1,2-CPDA: 11.5