BGC0000820: physostigmine biosynthetic gene cluster from Streptomyces griseofuscus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 8,547 nt. (total: 8,547 nt).
This entry is originally from NCBI GenBank KF201694.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000820
Short description physostigmine biosynthetic gene cluster from Streptomyces griseofuscus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Alkaloid
Loci NCBI GenBank: KF201694.1
Compounds
  • physostigmine
Species Streptomyces griseofuscus [taxonomy]
References
Chemical products information
physostigmine
Copy SMILES
C15H21N3O2
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AHL44339.1
  • psmA
 1 - 1008 (+) methyltransferase
copy AA seq
copy Nt seq
  • AHL44340.1
  • psmB
 1097 - 2026 (+) hydrolase
copy AA seq
copy Nt seq
  • AHL44341.1
  • psmC
 2060 - 2845 (+) methyltransferase
copy AA seq
copy Nt seq
  • AHL44342.1
  • psmD
 2861 - 3664 (+) methyltransferase
copy AA seq
copy Nt seq
  • AHL44343.1
  • psmE
 3668 - 5335 (+) carbamoyltransferase
copy AA seq
copy Nt seq
  • AHL44344.1
  • psmF
 5332 - 5880 (+) N-acetyltransferase
copy AA seq
copy Nt seq
  • AHL44345.1
  • psmG
 5864 - 7069 (+) putative tryptophan 2,3-dioxygenase
copy AA seq
copy Nt seq
  • AHL44346.1
  • psmH
 7066 - 8547 (+) PLP-dependent decarboxylase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 4IL6M35C3LCTFERWKJH5IZTU, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.