BGC0000869 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000869 (Nostoc sp. 'Peltigera membranacea cyanobiont')

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	hglE-KS,T1PKS	1	17,945	heterocyst glycolipids	other:other	100%

BGC0000869 - Region 1 - T1PKS,hglE-KS

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Location: 1 - 17,945 nt. (total: 17,945 nt) Show pHMM detection rules used

Region on contig edge.

hglE-KS: (hglE or hglD)
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 17,946
Label		BGC0000869

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000869	2.00	Other	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0000863	0.52	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000861	0.52	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0002648	0.52	Polyketide	eicosapentaenoic acid	Shewanella sp. N2AIL
BGC0000284	0.51	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0002429	0.50	Terpene, Polyketide	higginsianin B	Colletotrichum higginsianum IMI 349063
BGC0000862	0.50	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0002483	0.48	Polyketide	usnic acid	Cladonia uncialis subsp. uncialis
BGC0000056	0.48	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001872	0.47	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000869	1.00	Other	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0000863	0.60	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000861	0.59	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0002648	0.59	Polyketide	eicosapentaenoic acid	Shewanella sp. N2AIL
BGC0000284	0.59	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0002429	0.58	Terpene, Polyketide	higginsianin B	Colletotrichum higginsianum IMI 349063
BGC0000862	0.58	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0002483	0.57	Polyketide	usnic acid	Cladonia uncialis subsp. uncialis
BGC0000056	0.57	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001872	0.57	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 17945:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

hglE

PKS_AT (634..932): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 70.8%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 86.7
inactive: 32.0
Methoxymalonyl-CoA: 31.5
Methylmalonyl-CoA: 23.3
Isobutyryl-CoA: 15.1
CHC-CoA: 14.5
Propionyl-CoA: 12.2
fatty_acid: 11.2
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

hglC

PKS_AT (1085..1361): mxmal

ATSignature: (unknown)

No matches above 50%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 17.3
Isobutyryl-CoA: 12.4
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0