BGC0000878: puromycin biosynthetic gene cluster from Streptomyces alboniger
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Location: 1 - 9,120 nt. (total: 9,120 nt).
This entry is originally from NCBI GenBank X92429.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000878
Short description puromycin biosynthetic gene cluster from Streptomyces alboniger
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
X92429.1
via
Compounds
  • puromycin
Species Streptomyces alboniger [taxonomy]
References
Chemical products information
puromycin Evidence:
Copy SMILES
C22H29N7O5
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAA63157.1
  • orfA
 1 - 435 (+)
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    • CAA63158.1
    • napH
    		 720 - 2177 (+) N-acetylpuromycin N-acetylhydrolase
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      • CAA63159.1
      • pur7
      		 2170 - 2628 (+) NTP pyrophosphohydrolase
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        • CAA63160.1
        • pur10
        		 2713 - 3729 (+) Oxido-reductase
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          • CAA63161.1
          • pur6
          		 3762 - 6080 (+) Synthetase
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            • CAA63162.1
            • pur4
            		 6137 - 7426 (+) Amino-transferase
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              • CAA63163.1
              • pur5
              		 7483 - 8169 (+) N-methyl-transferase
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                • CAA63164.1
                • pur3
                		 8253 - 9074 (+) Mono-phosphatase
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                  Biosynthesis information
                  Annotation changelog

                  Entry version: 4

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-10-07
                  Update chemical activity to schema version 2.11
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 3

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-09-15
                  Updated bioactivity data
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 2

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2019-10-16
                  Migrated from v1.4
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2019-10-16
                  Updated compound(s) information (NPAtlas curation)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2015-06-12
                  Submitted
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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