BGC0000882: mildiomycin biosynthetic gene cluster from Streptomyces rimofaciens
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Location: 6,125 - 25,938 nt. (total: 19,814 nt).
This entry is originally from NCBI GenBank JN999998.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000882
Short description mildiomycin biosynthetic gene cluster from Streptomyces rimofaciens
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
JN999998.1
6125 - 25938
via
Compounds
  • mildiomycin
Species Streptomyces rimofaciens [taxonomy]
References
Chemical products information
mildiomycin Evidence:
Copy SMILES
C19H30N8O9
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACA14348.1
  • milA
 6125 - 7129 (+) CMP 5-hydroxymethylase
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    • ACA14349.1
    • MilB
    		 7252 - 7764 (+) CMP/hydroxymethyl CMP hydrolase
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      • AFD20743.1
      • milC
      		 7906 - 9168 (+) cytosylglucuronic acid/hydroxymethyl cytosylglucuronic acid synthase
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        • AFD20744.1
        • milD
        		 9185 - 10372 (+) degT/dnrJ/eryC1/strS aminotransferase
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          • AFD20745.1
          • milE
          		 10380 - 11201 (+) aminoglycoside phosphotransferase
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            • AFD20746.1
            • milF
            		 11194 - 11667 (+) hypothetical protein
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              • AFD20747.1
              • milG
              		 11627 - 12634 (+) radical SAM superfamily
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                • AFD20748.1
                • milH
                		 12729 - 14951 (+) MilH
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                  • AFD20749.1
                  • milI
                  		 14948 - 16030 (+) chitinase A precursor
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                    • AFD20750.1
                    • milJ
                    		 16202 - 17155 (+) predicted protein
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                      • AFD20751.1
                      • milK
                      		 17152 - 18480 (+) major facilitator superfamily
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                        • AFD20752.1
                        • milL
                        		 18488 - 19474 (+) hypothetical protein
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                          • AFD20753.1
                          • milM
                          		 19548 - 20717 (+) Aspartate/tyrosine/aromatic aminotransferase
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                            • AFD20754.1
                            • milN
                            		 20710 - 21486 (+) dihydrodipicolinate synthetase family protein
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                              • AFD20755.1
                              • milO
                              		 22219 - 23289 (-) regulatory protein LuxR family
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                                • AFD20756.1
                                • milP
                                		 23295 - 24878 (-) ABC transporter superfamily
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                                  • AFD20757.1
                                  • milQ
                                  		 25168 - 25938 (+) Aminoglycoside phosphotransferase
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                                    Biosynthesis information
                                    Annotation changelog

                                    Entry version: 4

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-10-07
                                    Update chemical activity to schema version 2.11
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 3

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-09-15
                                    Updated bioactivity data
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 2

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2019-10-16
                                    Migrated from v1.4
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    2019-10-16
                                    Updated compound(s) information (NPAtlas curation)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 1

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2015-06-12
                                    Submitted
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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