BGC0000893 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000893 (Streptomyces venezuelae ATCC 10712)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	22,006	caniferolide A / caniferolide B / caniferolide C / caniferolide D	Polyketide:Modular type I	3%

BGC0000893 - Region 1 - NRPS-like

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Location: 1 - 22,006 nt. (total: 22,006 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 22,007
Label		BGC0000893

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000893.1	1.00	NRP	chloramphenicol	Streptomyces venezuelae ATCC 10712
BGC0001831.1	0.23	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001366.1	0.21	Polyketide	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2
BGC0001399.1	0.20	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000343.1	0.19	NRP	enterobactin	Pseudomonas sp. J465
BGC0001824.1	0.18	NRP	xefoampeptides A-G	Xenorhabdus beddingii
BGC0001529.1	0.18	Alkaloid	bezastatin derivates	Streptomyces sp. RI18
BGC0001914.1	0.18	Other	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0001405.1	0.18	Polyketide	chaetoviridin E, 11-epichaetomugilin A	Chaetomium globosum CBS 148.51
BGC0001302.1	0.18	Other	lomofungin	Streptomyces lomondensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000893.1	1.00	NRP	chloramphenicol	Streptomyces venezuelae ATCC 10712
BGC0001831.1	0.56	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001366.1	0.54	Polyketide	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2
BGC0001399.1	0.52	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000343.1	0.51	NRP	enterobactin	Pseudomonas sp. J465
BGC0001824.1	0.50	NRP	xefoampeptides A-G	Xenorhabdus beddingii
BGC0001529.1	0.49	Alkaloid	bezastatin derivates	Streptomyces sp. RI18
BGC0001914.1	0.49	Other	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0001405.1	0.49	Polyketide	chaetoviridin E, 11-epichaetomugilin A	Chaetomium globosum CBS 148.51
BGC0001302.1	0.49	Other	lomofungin	Streptomyces lomondensis

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 22006:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (tyr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

SVEN_0922

Search NORINE for peptide: strict or relaxed

AMP-binding (12..392): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DASmecAVCK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 70% (weak)

SVEN_0927

Search NORINE for peptide: strict or relaxed

AMP-binding (10..384): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DINptGtIaK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 60% (weak)