BGC0000914 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000914 (Streptomyces coelicolor A3(2))

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	furan,butyrolactone	1	28,972	High	methylenomycin A	other:other

BGC0000914 - Region 1 - butyrolactone,furan

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Location: 1 - 28,972 nt. (total: 28,972 nt) Show pHMM detection rules used

Region on contig edge.

furan: (mmyO or AvrD)
butyrolactone: AfsA

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 28,973
Label		BGC0000914

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase

mmfH: acyl-CoA dehydrogenase type 2

smcogs: SMCOG1191: acyl-CoA dehydrogenase type 2

mmyE: NADH:flavin oxidoreductase/NADH oxidase

smcogs: SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase

mmyF: flavin reductase domain protein FMN-binding

smcogs: SMCOG1160: flavin reductase domain protein FMN-binding

mmyG: oxidoreductase

smcogs: SMCOG1079: oxidoreductase

Hydrolases: esterase

mmyT: thioesterase

smcogs: SMCOG1004: thioesterase

Ligases: synthase

mmyC: 3-oxoacyl-(acyl carrier protein) synthase III

smcogs: SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000914.5	1.56	other (other)	methylenomycin A	Streptomyces coelicolor A3(2)
BGC0000849.4	0.91	other (butyrolactone)	SCB1, SCB2, SCB3	Streptomyces coelicolor A3(2)
BGC0000848.5	0.88	other (other)	A-factor	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000850.5	0.69	other (other)	γ-butyrolactone	Streptomyces acidiscabies
BGC0000016.4	0.35	other (other)	amphotericin B	Streptomyces nodosus
BGC0002578.2	0.33	other (other)	gaburedin A, gaburedin B, gaburedin C, gaburedin D, gaburedin E, gaburedin F	Streptomyces venezuelae ATCC 10712
BGC0000277.5	0.22	PKS	urdamycin	Streptomyces fradiae
BGC0001771.4	0.21	NRPS	scleric acid	Streptomyces sclerotialus
BGC0002514.3	0.21	PKS	julichrome Q6.6	Streptomyces sampsonii
BGC0000665.5	0.21	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000914.5	1.00	other (other)	methylenomycin A	Streptomyces coelicolor A3(2)
BGC0000849.4	0.76	other (butyrolactone)	SCB1, SCB2, SCB3	Streptomyces coelicolor A3(2)
BGC0000848.5	0.75	other (other)	A-factor	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000850.5	0.68	other (other)	γ-butyrolactone	Streptomyces acidiscabies
BGC0000016.4	0.49	other (other)	amphotericin B	Streptomyces nodosus
BGC0002578.2	0.48	other (other)	gaburedin A, gaburedin B, gaburedin C, gaburedin D, gaburedin E, gaburedin F	Streptomyces venezuelae ATCC 10712
BGC0002554.2	0.45	other (other)	carquinostatin A, carquinostatin B	Streptomyces exfoliatus
BGC0001903.3	0.44	other (other)	neocarazostatin A	Streptomyces sp. MA37
BGC0002711.2	0.44	PKS	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0000204.5	0.43	PKS	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200

Similar known clusters from MIBiG 4.0