BGC0000921: promysalin biosynthetic gene cluster from Pseudomonas putida
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Location: 4,335 - 20,085 nt. (total: 15,751 nt).
This entry is originally from NCBI GenBank GU211010.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Polyketide
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000921
Short description promysalin biosynthetic gene cluster from Pseudomonas putida
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other (Shikimate-derived)
  • Polyketide
  • NRP
Loci NCBI GenBank: GU211010.1
Compounds
  • promysalin
Species Pseudomonas putida [taxonomy]
References
Chemical products information
promysalin
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C26H38N2O6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADQ74607.1
  • ppgO
 4335 - 6323 (-) glutamine amidotransferase
  • Tailoring (Amination)
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  • ADQ74608.1
  • ppgN
 6361 - 7359 (-) Rieske [2Fe-2S] domain protein
  • Tailoring (Hydroxylation)
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  • ADQ74609.1
  • ppgA
 7778 - 8011 (+) carrier protein
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  • ADQ74610.1
  • ppgB
 8004 - 8771 (+) hypothetical protein
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  • ADQ74611.1
  • ppgC
 8791 - 9093 (+) acyl carrier protein
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  • ADQ74612.1
  • ppgD
 9090 - 9542 (+) beta-hydroxymyristoyl-acyl carrier protein dehydratase
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  • ADQ74613.1
  • ppgE
 9539 - 10525 (+) beta-ketoacyl synthase
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  • ADQ74614.1
  • ppgF
 10533 - 11525 (+) Rieske [2Fe-2S] domain protein
  • Scaffold biosynthesis
Sequence-based prediction
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  • ADQ74615.1
  • ppgG
 11592 - 11903 (+) isochorismate-pyruvate lyase
  • Scaffold biosynthesis
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  • ADQ74616.1
  • ppgH
 11900 - 13309 (+) isochorismate synthase
  • Scaffold biosynthesis
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  • ADQ74617.1
  • ppgI
 13347 - 14189 (+) metal-dependent hydrolase
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  • ADQ74618.1
  • ppgJ
 14216 - 15997 (+) amino acid adenylation protein
  • Scaffold biosynthesis
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  • ADQ74619.1
  • ppgK
 16011 - 17207 (+) beta-ketoacyl synthase
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  • ADQ74620.1
  • ppgL
 17204 - 18469 (+) BAHD family acyl transferase
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  • ADQ74621.1
  • ppgM
 18466 - 20040 (+) salicylyl-AMP ligase
  • Scaffold biosynthesis
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Polyketide-specific information
Subclass Unknown
Cyclic? no
Polyketide-synthases
Genes Properties Modules
ppgK Synthase subclass:
Module 1
Genes: ppgK
Core domains: Ketosynthase
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ppgJ
Module 0
Specificity: proline
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: KA3LORKD7MC3PYJEVNTA5TBS, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Removed ketoreductase stereochemistry annotation from modules without ketoreductases
  • Changed amino acid substrates to lower case
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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