BGC0000949: A-500359 A biosynthetic gene cluster from Streptomyces griseus
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Location: 1 - 65,257 nt. (total: 65,257 nt).
This entry is originally from NCBI GenBank AB476988.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000949
Short description A-500359 A biosynthetic gene cluster from Streptomyces griseus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AB476988.1
via
Compounds
  • A-500359 A
  • A-500359 B
Species Streptomyces griseus [taxonomy]
References
Chemical products information
A-500359 A Evidence:
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C24H33N5O12
A-500359 B Evidence:
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C23H31N5O12
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAI23310.1
 889 - 1626 (+) putative deoxyribonuclease
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    • BAI23311.1
    		 3910 - 6603 (+) putative endonuclease
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      • BAI23312.1
      		 7947 - 8504 (-) putative terminal protein
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        • BAI23313.1
        		 8517 - 10751 (-) putative telomere associated protein
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          • BAI23314.1
          		 11410 - 11856 (-) unknown
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            • BAI23315.1
            		 15076 - 15957 (-) putative dioxygenase
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              • BAI23316.1
              		 15973 - 16881 (-) putative carbamoyl transferase
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                • BAI23317.1
                		 16900 - 17850 (-) putative 3-ketoreductase
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                  • BAI23318.1
                  		 17864 - 18838 (-) putative clavaminic synthase
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                    • BAI23319.1
                    		 18869 - 20266 (-) putative 2,3-dehydratase
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                      • BAI23320.1
                      		 20312 - 21253 (-) putative 4-epimerase
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                        • BAI23321.1
                        		 22569 - 23720 (-) putative glycosyltransferase
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                          • BAI23322.1
                          		 23742 - 25127 (-) putative serine hydroxymethyltransferase
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                            • BAI23323.1
                            		 25311 - 25574 (+) putative pyrophosphatase
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                              • BAI23324.1
                              		 25612 - 27891 (+) putative carbonmonoxide dehydrogenase
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                                • BAI53084.1
                                		 27888 - 28622 (+) putative O-methyltransferase
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                                  • BAI23325.1
                                  		 28657 - 29163 (+) putative carbonmonoxide dehydrogenase
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                                    • BAI23326.1
                                    		 29222 - 30091 (+) putative carbonmonoxide dehydrogenase
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                                      • BAI23327.1
                                      		 30214 - 32034 (+) putative ABC-transporter
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                                        • BAI23328.1
                                        		 32031 - 33980 (+) putative ABC-transporter
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                                          • BAI23329.1
                                          		 34843 - 35847 (-) putative aminoglycoside phosphotransferase
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                                            • BAI23330.1
                                            		 35823 - 36788 (-) putative 4,6-dehydratase
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                                              • BAI23331.1
                                              		 36773 - 37843 (-) putative thymidylyltransferase
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                                                • BAI23332.1
                                                		 38277 - 39044 (+) putative methyltransferase
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                                                  • BAI23333.1
                                                  		 39118 - 41055 (+) putative C-methyltransferase
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                                                    • BAI23334.1
                                                    		 42329 - 45592 (+) putative non-ribosomal peptide synthetase
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                                                      • BAI23335.1
                                                      		 45573 - 46982 (+) putative non-ribosomal peptide synthetase
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                                                        • BAI23336.1
                                                        		 47046 - 48254 (+) putative beta-lactamase
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                                                          • BAI23337.1
                                                          		 48775 - 49212 (+) putative DNA ligase
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                                                            • BAI23338.1
                                                            		 50474 - 51250 (+) putative ABC-transporter
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                                                              • BAI23339.1
                                                              		 53401 - 54099 (+) putative transposase
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                                                                • BAI23340.1
                                                                		 54064 - 54819 (-) putative transposase
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                                                                  • BAI23341.1
                                                                  		 54901 - 55386 (+) unknown
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                                                                    • BAI23342.1
                                                                    		 59521 - 60180 (-) putative endonuclease
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                                                                      • BAI23343.1
                                                                      		 60941 - 62227 (-) putative transporter
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                                                                        • BAI23344.1
                                                                        		 62316 - 62783 (+) putative transcriptional regulator
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                                                                          • BAI23345.1
                                                                          		 63348 - 63746 (-) putative regulatory protein
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                                                                            Biosynthesis information
                                                                            Annotation changelog

                                                                            Entry version: 4

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2022-10-07
                                                                            Update chemical activity to schema version 2.11
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 3

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2022-09-15
                                                                            Updated bioactivity data
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 2

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2019-10-16
                                                                            Migrated from v1.4
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 1

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2015-06-12
                                                                            Submitted
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            Detailed domain annotation
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