BGC0000953: amicetin biosynthetic gene cluster from Streptomyces vinaceusdrappus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 37,337 nt. (total: 37,337 nt).
This entry is originally from NCBI GenBank HM748814.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Saccharide
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000953
Short description amicetin biosynthetic gene cluster from Streptomyces vinaceusdrappus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Saccharide (aminoglycoside)
Loci NCBI GenBank: HM748814.1
Compounds
  • amicetin
Species Streptomyces vinaceusdrappus [taxonomy]
References
Chemical products information
amicetin
Copy SMILES
C29H42N6O9
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEF16063.1
 1930 - 2970 (+) putative transcription antitermination regulator
copy AA seq
copy Nt seq
  • AEF16062.1
 4876 - 6066 (+) Mg or Mn-dependent protein phosphatase
copy AA seq
copy Nt seq
  • AEF16040.1
  • amiA
 7917 - 8711 (+) PabC
copy AA seq
copy Nt seq
  • AEF16041.1
  • amiB
 9160 - 10278 (+) NDP-sugar aminotransferase
copy AA seq
copy Nt seq
  • AEF16042.1
  • amic
 10275 - 11651 (+) NDP-hexose 2,3-dehydratase
copy AA seq
copy Nt seq
  • AEF16043.1
  • amiD
 11648 - 12616 (+) NDP-hexose 3-ketoreductase
copy AA seq
copy Nt seq
  • AEF16044.1
  • amiE
 12778 - 13551 (+) glucose-1-phosphate thymidylyltransferase
  • Precursor biosynthesis
Activity assay
copy AA seq
copy Nt seq
  • AEF16045.1
  • amiF
 13592 - 14998 (+) GCN5-like N-acetyltransferase
copy AA seq
copy Nt seq
  • AEF16046.1
  • amiG
 15035 - 16522 (+) glycosyltransferase
  • Tailoring (Glycosylation)
Activity assay
Knock-out
copy AA seq
copy Nt seq
  • AEF16047.1
  • amiH
 16530 - 17279 (+) NDP-aminohexose N-dimethyltransferase
  • Tailoring (Methylation)
Knock-out
copy AA seq
copy Nt seq
  • AEF16048.1
  • amiI
 17276 - 17824 (+) deoxy cytidine deoxyribosyltransferase
copy AA seq
copy Nt seq
  • AEF16049.1
  • amiJ
 17821 - 19032 (+) cytosylglucuronic acid synthase/glycosyltransferase
copy AA seq
copy Nt seq
  • AEF16050.1
  • amiK
 19048 - 19995 (+) NDP-hexose 4-ketoreductase
copy AA seq
copy Nt seq
  • AEF16051.1
  • amiL
 20038 - 21534 (+) benzoate-CoA synthase
  • Precursor biosynthesis
Knock-out
copy AA seq
copy Nt seq
  • AEF16052.1
  • amiM
 21531 - 23564 (+) PABA synthase
copy AA seq
copy Nt seq
  • AEF16053.1
  • amiN
 23609 - 24928 (+) CDP-4-keto-6-deoxyglucose-3-dehydratase
copy AA seq
copy Nt seq
  • AEF16054.1
  • amiO
 24970 - 26649 (+) ABC transporter
copy AA seq
copy Nt seq
  • AEF16055.1
  • amiP
 26996 - 27634 (+) TetR family transcriptional regulator
copy AA seq
copy Nt seq
  • AEF16056.1
  • amiQ
 27684 - 28877 (+) major facilitator superfamily transporter
copy AA seq
copy Nt seq
  • AEF16057.1
  • amiR
 28935 - 29834 (+) malonyl CoA-acyl carrier protein transacylase
  • Tailoring (Acylation)
Knock-out
copy AA seq
copy Nt seq
  • AEF16058.1
  • amiS
 29925 - 31283 (+) glycine/serine hydroxymethyltransferase
copy AA seq
copy Nt seq
  • AEF16059.1
  • amiT
 31329 - 33794 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • AEF16060.1
  • amiU
 33825 - 34889 (+) dTDP glucose 4,6-dehydratase
copy AA seq
copy Nt seq
  • AEF16061.1
 35653 - 36192 (-) GCN5-like N-acetyltransferase
copy AA seq
copy Nt seq
Saccharide-specific information
Subclass aminoglycoside
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: YU43TGF6RSKW2WJOQIFYBQO4, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.