BGC0000981: cylindrospermopsin biosynthetic gene cluster from Aphanizomenon sp. 10E6
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Location: 1 - 57,112 nt. (total: 57,112 nt).
This entry is originally from NCBI GenBank GQ385961.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000981
Short description cylindrospermopsin biosynthetic gene cluster from Aphanizomenon sp. 10E6
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
GQ385961.1
via
Compounds
  • cylindrospermopsin
Species Aphanizomenon sp. 10E6 [taxonomy]
References
Chemical products information
cylindrospermopsin Evidence:
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C15H21N5O7S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADF88266.1
 190 - 1092 (+) RNA-binding S1 domain-containing protein
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    • ADF88267.1
    		 1374 - 3617 (+) oxidoreductase alpha subunit
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      • ADF88268.1
      		 4170 - 5810 (-) transposase
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        • ADF88269.1
        		 6213 - 6536 (+) hypothetical protein
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          • ADF88270.1
          • cyrJ
          		 7145 - 7930 (-) putative sulfotransferase
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            • ADF88271.1
            • cyrH
            		 8933 - 10363 (-) aminohydrolase
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              • ADF88272.1
              • cyrK
              		 10809 - 12248 (+) multidrug exporter MatE
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                • ADF88273.1
                • cyrI
                		 13364 - 14194 (-) proline dioxygenase-like protein
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                  • ADF88274.1
                  • cyrG
                  		 14248 - 15684 (-) putative uracil ring formation
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                    • ADF88275.1
                    • cyrF
                    		 15903 - 19976 (-) polyketide synthase
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                      • ADF88276.1
                      • cyrD
                      		 20032 - 25587 (-) polyketide synthase
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                        • ADF88277.1
                        • cyrC
                        		 25587 - 30590 (-) polyketide synthase
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                          • ADF88278.1
                          • cyrA
                          		 31142 - 32317 (+) amidinotransferase
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                            • ADF88279.1
                            • cyrB
                            		 32332 - 41085 (+) mixed NRPS/PKS
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                              • ADF88280.1
                              • cyrE
                              		 41090 - 46756 (+) polyketide synthase
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                                • ADF88281.1
                                		 47180 - 47623 (+) hypothetical protein
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                                  • ADF88282.1
                                  		 47667 - 48065 (-) hypothetical protein
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                                    • ADF88283.1
                                    		 49222 - 49599 (+) hypothetical protein
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                                      • ADF88284.1
                                      		 49808 - 50167 (+) hypothetical protein
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                                        • ADF88285.1
                                        		 50265 - 50612 (+) hypothetical protein
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                                          • ADF88286.1
                                          		 50678 - 51079 (+) hypothetical protein
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                                            • ADF88287.1
                                            		 51719 - 52795 (-) putative nucleotidyl transferase
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                                              • ADF88288.1
                                              		 53153 - 54658 (+) putative cell envelope-like transcriptional attenuator
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                                                • ADF88289.1
                                                		 54745 - 55251 (+) pentapeptide repeat-containing protein
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                                                  • ADF88290.1
                                                  		 55715 - 56914 (+) putative integral membrane protein MviN
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                                                    Biosynthesis information
                                                    Annotation changelog

                                                    Entry version: 2

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2019-10-16
                                                    Migrated from v1.4
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 1

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2015-06-12
                                                    Submitted
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    Detailed domain annotation
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