BGC0000990: epothilone biosynthetic gene cluster from Sorangium cellulosum
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Location: 1 - 72,852 nt. (total: 72,852 nt).
This entry is originally from NCBI GenBank GU063811.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000990
Short description epothilone biosynthetic gene cluster from Sorangium cellulosum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
GU063811.1
via
Compounds
  • epothilone
Species Sorangium cellulosum [taxonomy]
References
Chemical products information
epothilone Evidence:
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C27H41N1O6S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADB12488.1
  • epoA
 437 - 4702 (+) EpoA
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    • ADB12489.1
    • epoB
    		 4699 - 8931 (+) EpoB
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      • ADB12490.1
      • epoC
      		 9078 - 14576 (+) EpoC
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        • ADB12491.1
        • epoD
        		 14573 - 36346 (+) EpoD
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          • ADB12492.1
          • epoE
          		 36351 - 47747 (+) EpoE
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            • ADB12493.1
            • epoF
            		 47762 - 55081 (+) EpoF
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              • ADB12494.1
              • epoK
              		 55196 - 56455 (+) EpoK
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                • ADB12495.1
                		 56633 - 57172 (+) hypothetical protein
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                  • ADB12496.1
                  		 57202 - 57759 (+) hypothetical protein
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                    • ADB12497.1
                    		 57847 - 58701 (-) hypothetical protein
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                      • ADB12498.1
                      		 58713 - 59180 (-) hypothetical protein
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                        • ADB12499.1
                        		 59531 - 59980 (+) hypothetical protein
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                          • ADB12500.1
                          		 60188 - 61105 (+) cation efflux protein
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                            • ADB12501.1
                            		 61505 - 61903 (+) type I restriction-modification system endonuclease
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                              • ADB12502.1
                              		 62141 - 62791 (+) hypothetical protein
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                                • ADB12503.1
                                		 62812 - 65931 (+) putative iron-sulfur binding oxidoreductase
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                                  • ADB12504.1
                                  		 65935 - 67296 (+) NrfD family oxidoreductase
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                                    • ADB12505.1
                                    		 67296 - 67832 (+) hypothetical protein
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                                      • ADB12506.1
                                      		 67829 - 68455 (+) hypothetical protein
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                                        • ADB12507.1
                                        		 68452 - 69633 (+) hypothetical protein
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                                          • ADB12508.1
                                          		 69633 - 70001 (+) hypothetical protein
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                                            • ADB12509.1
                                            		 69998 - 70951 (+) hypothetical protein
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                                              • ADB12510.1
                                              • COII
                                              		 70948 - 72111 (+) cytochrome c oxidase subunit II
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                                                • ADB12511.1
                                                • COI
                                                		 72108 - >72852 (+) cytochrome c oxidase subunit I
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                                                  Biosynthesis information

                                                  No biosynthesis information available for this record.

                                                  Annotation changelog

                                                  Entry version: 2

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2019-10-16
                                                  Migrated from v1.4
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  2019-10-16
                                                  Updated reference publication(s) (MIBiG Annotathon)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 1

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2015-06-12
                                                  Submitted
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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