Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000998.1:
Cluster 1NRP / Polyketide151101

BGC0000998, guadinomine biosynthetic gene cluster from Streptomyces sp. K01-0509. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: guadinomine

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

guadinomine (BGC0000998). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank JX545234. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Holmes TC et al. (2012) Molecular insights into the biosynthesis of guadinomine: a type III secretion system inhibitor. J Am Chem Soc 134(42):17797-806. doi: 10.1021/ja308622d. Epub 2012