BGC0001013: meridamycin biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 116,856 nt. (total: 116,856 nt).
This entry is originally from NCBI GenBank DL080157.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0001013
Short description meridamycin biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
DL080157.1
via
Compounds
  • meridamycin
Species Streptomyces sp. [taxonomy]
References
Chemical products information
meridamycin Evidence:
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C45H75N1O12
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ctg1_orf1
 1 - 231 (+)
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    • ctg1_orf2
    		 221 - 1108 (+)
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      • ctg1_orf3
      		 1265 - 2830 (+)
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        • ctg1_orf4
        		 2827 - 3483 (+)
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          • ctg1_orf5
          		 3885 - 4727 (+)
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            • ctg1_orf6
            		 4790 - 6673 (+)
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              • ctg1_orf7
              		 6878 - 7762 (+)
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                • ctg1_orf8
                		 7784 - 8977 (+)
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                  • ctg1_orf9
                  		 9304 - 10248 (+)
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                    • ctg1_orf10
                    		 10337 - 10960 (+)
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                      • ctg1_orf11
                      		 11037 - 12485 (+)
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                        • ctg1_orf12
                        		 12509 - 12673 (+)
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                          • ctg1_orf13
                          		 12677 - 14863 (+)
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                            • ctg1_orf14
                            		 14919 - 16517 (+)
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                              • ctg1_orf15
                              		 16548 - 17423 (+)
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                                • ctg1_orf16
                                		 17420 - 18376 (+)
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                                  • ctg1_orf17
                                  		 18381 - 19724 (+)
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                                    • ctg1_orf18
                                    		 19942 - 20940 (+)
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                                      • ctg1_orf19
                                      		 21638 - 26311 (+)
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                                        • ctg1_orf20
                                        		 26335 - 43422 (+)
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                                          • ctg1_orf21
                                          		 43480 - 64788 (+)
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                                            • ctg1_orf22
                                            		 64785 - 88691 (+)
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                                              • ctg1_orf23
                                              		 88681 - 98352 (+)
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                                                • ctg1_orf24
                                                		 98393 - 99586 (+)
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                                                  • ctg1_orf25
                                                  		 99736 - 100167 (+)
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                                                    • ctg1_orf26
                                                    		 100278 - 100814 (+)
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                                                      • ctg1_orf27
                                                      		 101050 - 101175 (+)
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                                                        • ctg1_orf28
                                                        		 101214 - 102698 (+)
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                                                          • ctg1_orf29
                                                          		 102817 - 103305 (+)
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                                                            • ctg1_orf30
                                                            		 103378 - 104232 (+)
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                                                              • ctg1_orf31
                                                              		 104343 - 105272 (+)
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                                                                • ctg1_orf32
                                                                		 105382 - 106152 (+)
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                                                                  • ctg1_orf33
                                                                  		 106319 - 107389 (+)
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                                                                    • ctg1_orf34
                                                                    		 107438 - 107896 (+)
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                                                                      • ctg1_orf35
                                                                      		 107930 - 109423 (+)
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                                                                        • ctg1_orf36
                                                                        		 109420 - 110061 (+)
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                                                                          • ctg1_orf37
                                                                          		 110151 - 111056 (+)
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                                                                            • ctg1_orf38
                                                                            		 111218 - 111718 (+)
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                                                                              • ctg1_orf39
                                                                              		 111715 - 113226 (+)
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                                                                                • ctg1_orf40
                                                                                		 113276 - 113734 (+)
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                                                                                  • ctg1_orf41
                                                                                  		 113916 - 116315 (+)
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                                                                                    • ctg1_orf42
                                                                                    		 116442 - 116855 (+)
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                                                                                      Biosynthesis information
                                                                                      Annotation changelog

                                                                                      Entry version: 4

                                                                                      Date
                                                                                      Changes
                                                                                      Submitters
                                                                                      Reviewers
                                                                                      2022-10-07
                                                                                      Update chemical activity to schema version 2.11
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                      Entry version: 3

                                                                                      Date
                                                                                      Changes
                                                                                      Submitters
                                                                                      Reviewers
                                                                                      2022-09-15
                                                                                      Removed empty gene annotations
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      2022-09-15
                                                                                      Updated bioactivity data
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                      Entry version: 2

                                                                                      Date
                                                                                      Changes
                                                                                      Submitters
                                                                                      Reviewers
                                                                                      2019-10-16
                                                                                      Migrated from v1.4
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      2019-10-16
                                                                                      Updated reference publication(s) (MIBiG Annotathon)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                      Entry version: 1

                                                                                      Date
                                                                                      Changes
                                                                                      Submitters
                                                                                      Reviewers
                                                                                      2015-06-12
                                                                                      Submitted
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      Detailed domain annotation
                                                                                      Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
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                                                                                      Similar known gene clusters from MIBiG 4.0
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                                                                                      Modifications to original record
                                                                                      • ctg1_orf1 was added
                                                                                      • ctg1_orf2 was added
                                                                                      • ctg1_orf3 was added
                                                                                      • ctg1_orf4 was added
                                                                                      • ctg1_orf5 was added
                                                                                      • ctg1_orf6 was added
                                                                                      • ctg1_orf7 was added
                                                                                      • ctg1_orf8 was added
                                                                                      • ctg1_orf9 was added
                                                                                      • ctg1_orf10 was added
                                                                                      • ctg1_orf11 was added
                                                                                      • ctg1_orf12 was added
                                                                                      • ctg1_orf13 was added
                                                                                      • ctg1_orf14 was added
                                                                                      • ctg1_orf15 was added
                                                                                      • ctg1_orf16 was added
                                                                                      • ctg1_orf17 was added
                                                                                      • ctg1_orf18 was added
                                                                                      • ctg1_orf19 was added
                                                                                      • ctg1_orf20 was added
                                                                                      • ctg1_orf21 was added
                                                                                      • ctg1_orf22 was added
                                                                                      • ctg1_orf23 was added
                                                                                      • ctg1_orf24 was added
                                                                                      • ctg1_orf25 was added
                                                                                      • ctg1_orf26 was added
                                                                                      • ctg1_orf27 was added
                                                                                      • ctg1_orf28 was added
                                                                                      • ctg1_orf29 was added
                                                                                      • ctg1_orf30 was added
                                                                                      • ctg1_orf31 was added
                                                                                      • ctg1_orf32 was added
                                                                                      • ctg1_orf33 was added
                                                                                      • ctg1_orf34 was added
                                                                                      • ctg1_orf35 was added
                                                                                      • ctg1_orf36 was added
                                                                                      • ctg1_orf37 was added
                                                                                      • ctg1_orf38 was added
                                                                                      • ctg1_orf39 was added
                                                                                      • ctg1_orf40 was added
                                                                                      • ctg1_orf41 was added
                                                                                      • ctg1_orf42 was added