BGC0001122: dihydroisoflavipucine biosynthetic gene cluster from Aspergillus terreus NIH2624
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Location: 901,119 - 944,781 nt. (total: 43,663 nt).
This entry is originally from NCBI GenBank CH476594.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001122
Short description dihydroisoflavipucine biosynthetic gene cluster from Aspergillus terreus NIH2624
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Iterative type I)
Loci
CH476594.1
901119 - 944781
via Knock-out studies, Gene expression correlated with compound production
Compounds
  • dihydroisoflavipucine
  • isoflavipucine
Species Aspergillus terreus NIH2624 [taxonomy]
References
Chemical products information
dihydroisoflavipucine Evidence:
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C12H17N1O4
Chemical database entries
NPAtlas
isoflavipucine Evidence:
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C12H15N1O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATEG_00316
  • EAU38962.1
 901119 - 902332 (-) conserved hypothetical protein
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    • ATEG_00317
    • EAU38963.1
    		 902628 - 904618 (+) conserved hypothetical protein
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      • ATEG_00318
      • EAU38964.1
      		 905023 - 906498 (+) conserved hypothetical protein
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        • ATEG_00319
        • EAU38965.1
        		 907326 - 910637 (-) predicted protein
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          • ATEG_00320
          • EAU38966.1
          		 911158 - 913578 (-) heat shock protein 78, mitochondrial precursor
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            • ATEG_00321
            • EAU38967.1
            		 914036 - 915078 (+) elongation factor 1-beta
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              • ATEG_00322
              • EAU38968.1
              		 915466 - 916188 (+) conserved hypothetical protein
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                • ATEG_00323
                • EAU38969.1
                		 917231 - 917761 (+) predicted protein
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                  • ATEG_00324
                  • EAU38970.1
                  		 918123 - 919320 (-) ubiquitin-conjugating enzyme E2S
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                    • ATEG_00325
                    • EAU38971.1
                    		 919949 - 931962 (-) PKS-NRPS hybrid
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                      • ATEG_00326
                      • EAU38972.1
                      		 933368 - 934642 (-) transcription factor
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                        • ATEG_00327
                        • EAU38973.1
                        		 936762 - 938081 (-) predicted protein
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                          • ATEG_00328
                          • EAU38974.1
                          		 938542 - 939854 (-) predicted protein
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                            • ATEG_00329
                            • EAU38975.1
                            		 940702 - 941242 (-) predicted protein
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                              • ATEG_00330
                              • EAU38976.1
                              		 941766 - 942314 (-) predicted protein
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                                • ATEG_00331
                                • EAU38977.1
                                		 942877 - 944781 (+) predicted protein
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                                  Biosynthesis information

                                  Biosynthetic modules

                                  Name
                                  1
                                  Type
                                  nrps-type1
                                  Genes
                                  ATEG_00325
                                  Substrates
                                  leucine (evidence: )
                                  Integrated Monomers
                                  Domains
                                  condensation, adenylation
                                  Annotation changelog

                                  Entry version: next

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2024-08-01
                                  MIBiG v4 annotathon
                                  • (ID: JXNPUXPAL6VYCS4XEXVRJDGK)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 3

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2022-09-15
                                  Corrected NRP module activity
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  2022-09-15
                                  Corrected gene identifiers
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  2022-09-15
                                  Changed amino acid substrates to lower case
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 2

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2019-10-16
                                  Migrated from v1.4
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  2019-10-16
                                  Updated compound(s) information (NPAtlas curation)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 1

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2015-06-12
                                  Submitted
                                  • (ID: ZUAEFEJPIFGA5SNZGJWBG3IU)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  Detailed domain annotation
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