Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001122.1:
Cluster 1NRP / Polyketide143663

BGC0001122, isoflavipucine biosynthetic gene cluster from Aspergillus terreus. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: dihydroisoflavipucine
SMILES string: Copy to clipboard
Molecular formula: C12H17NO4
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Other (linear)
Thioesterase type:
None
Release / cyclization type:
Unknown

Nonribosomal peptide synthetases:
ATEG_00325 (EAU38971)
Module 1
A specificity: Leucine
Evidence for specificity: Other
C domain subtype: Unknown
Polyketide subclass:
Other (linear)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
EAU38971
Iterative PKS subtype:
Non-reducing
Number of iterations:
2
Other
Thioesterase type:
None
Release / cyclization type:
Unknown

Gene cluster description

isoflavipucine (BGC0001122). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank CH476594, positions 919949-944781. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Knock-out studies, Gene expression correlated with compound production
MIxS-compliance:Unknown
Contact for this cluster:Yuta Tsunematsu (University of Shizuoka)

Literature references

1. Gressler M et al. (2011) Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus. Chem Biol 18(2):198-209. doi: 10.1016/j.chembiol.2010.12.011. Epub