BGC0001132: xenotetrapeptide biosynthetic gene cluster from Xenorhabdus nematophila ATCC 19061
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Location: 1,902,005 - 1,914,421 nt. (total: 12,417 nt).
This entry is originally from NCBI GenBank FN667742.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001132
Short description xenotetrapeptide biosynthetic gene cluster from Xenorhabdus nematophila ATCC 19061
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
FN667742.1
1902005 - 1914421
via Knock-out studies, Heterologous expression
Compounds
  • xenotetrapeptide
Species Xenorhabdus nematophila ATCC 19061 [taxonomy]
References
Chemical products information
xenotetrapeptide Evidence:
Copy SMILES
C21H38N4O4
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • XNC1_2022
  • CBJ90082.1
1902005 - 1914421 (+) Non Ribosomal peptide synthetase (-succinylbenzoate--CoA ligase)
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    Biosynthesis information

    Biosynthetic modules

    Name
    1
    Type
    nrps-type1
    Genes
    XNC1_2022
    Substrates
    valine (evidence: Structure-based inference)
    Integrated Monomers
    Domains
    condensation (LCL), adenylation, epimerase
    Name
    2
    Type
    nrps-type1
    Genes
    XNC1_2022
    Substrates
    leucine (evidence: Structure-based inference)
    Integrated Monomers
    Domains
    condensation (Dual), adenylation
    Name
    3
    Type
    nrps-type1
    Genes
    XNC1_2022
    Substrates
    valine (evidence: Structure-based inference)
    Integrated Monomers
    Domains
    condensation (LCL), adenylation, epimerase
    Name
    4
    Type
    nrps-type1
    Genes
    XNC1_2022
    Substrates
    valine (evidence: Structure-based inference)
    Integrated Monomers
    Domains
    condensation (Dual), adenylation
    Annotation changelog

    Entry version: 3

    Date
    Changes
    Submitters
    Reviewers
    Corrected NRP module activity
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
    Changed amino acid substrates to lower case
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

    Entry version: 2

    Date
    Changes
    Submitters
    Reviewers
    Migrated from v1.4
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

    Entry version: 1

    Date
    Changes
    Submitters
    Reviewers
    Submitted
    • (ID: SCFYH7235HZBUM2XBV52IUHT)
    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
    Detailed domain annotation
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