BGC0001141 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001141 (Penicillium brefeldianum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	37,663

BGC0001141 - Region 1 - T1PKS

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Location: 1 - 37,663 nt. (total: 37,663 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 37,664
Label		BGC0001141

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001141.1	1.00	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0001280.1	0.30	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.30	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001068.1	0.29	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001858.1	0.28	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001475.1	0.27	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0000003.1	0.26	Polyketide	AF-toxin	Alternaria alternata
BGC0001277.1	0.24	Terpene	nivalenol, vomitoxin, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, neosolaniol, calonectrin, apotrichodiol, isotrichotriol, 15-deacetylcalonectrin, T-2 toxin, 3-acetyl T-2 toxin, trichodiene	Fusarium graminearum
BGC0001892.1	0.24	Polyketide	botcinic acid	Botrytis cinerea B05.10
BGC0001969.1	0.24	Terpene	asperterpenoid A	Talaromyces wortmannii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001141.1	1.00	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0001280.1	0.64	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.64	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001068.1	0.63	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001858.1	0.62	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001475.1	0.60	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0000003.1	0.59	Polyketide	AF-toxin	Alternaria alternata
BGC0001277.1	0.58	Terpene	nivalenol, vomitoxin, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, neosolaniol, calonectrin, apotrichodiol, isotrichotriol, 15-deacetylcalonectrin, T-2 toxin, 3-acetyl T-2 toxin, trichodiene	Fusarium graminearum
BGC0001892.1	0.58	Polyketide	botcinic acid	Botrytis cinerea B05.10
BGC0001969.1	0.57	Terpene	asperterpenoid A	Talaromyces wortmannii

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 37663:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

AIA58899.1

PKS_AT (559..872): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; 2-Methylbutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 77.6
Methoxymalonyl-CoA: 68.7
Malonyl-CoA: 66.6
Ethylmalonyl-CoA: 44.9
Propionyl-CoA: 41.3
trans-1,2-CPDA: 38.2
Isobutyryl-CoA: 36.8
2-Methylbutyryl-CoA: 34.1
fatty_acid: 31.1
CHC-CoA: 22.1
Benzoyl-CoA: 14.5
3-Methylbutyryl-CoA: 14.4
Acetyl-CoA: 9.7
inactive: 0.0